Learning Session 7: Complex Interventions in Learning Health Systems

4/19/21

PRESENTER: Gregory Tasian, MD, MSc, MSCE Children's Hospital of Philadelphia

LEARNING OBJECTIVES

Participants will be able to:

To learn the characteristics of complex interventions
To understand the purpose and structure of process evaluations of complex interventions

REFERENCES

The PCORI Methodology Standards. (2019). Standard 13: Standards for Studies of Complex Interventions. Methodology Committee of the Patient-Centered Outcomes Research Institute (PCORI). Available at: https://www.pcori.org/sites/default/files/PCORI-Methodology-Standards.pdf

De Silva, M. J., Breuer, E., Lee, L., Asher, L., Chowdhary, N., Lund, C., & Patel, V. (2014). Theory of change: A theory-driven approach to enhance the medical Research Council's framework for Complex interventions. Trials,15(1). doi:10.1186/1745-6215-15-267. Available at: https://trialsjournal.biomedcentral.com/articles/10.1186/1745-6215-15-267

Harvey, L. A., & Jan, S. (2017). Process evaluations for large clinical trials involving complex interventions. Spinal Cord,55(11), 963-963. doi:10.1038/sc.2017.107. Available at: https://www.nature.com/articles/sc2017107

Petticrew, M. (2011). When are complex interventions 'complex'? When are simple interventions 'simple'? The European Journal of Public Health, 21(4), 397-398. doi:10.1093/eurpub/ckr084. Available at: https://academic.oup.com/eurpub/article/21/4/397/438290

Skeels, S. E., Pernigotti, D., Houlihan, B. V., Belliveau, T., Brody, M., Zazula, J., Hasiotis, S., Seetharama S., Rosenblum, D., Jette, A. (2017). Sci peer health coach influence on self-management with peers: A qualitative analysis. Spinal Cord, 55(11), 1016-1022. doi:10.1038/sc.2017.104. Available at: https://www.nature.com/articles/sc2017104

Moore, G. F., Audrey, S., Barker, M., Bond, L., Bonell, C., Hardeman, W., Moore, L., O'Cathain, A., Baird, J. (2015). Process evaluation of complex interventions: Medical Research Counsel Guidance. BMJ, 350(Mar19 6). doi:10.1136/bmj.h1258. Available at: https://www.bmj.com/content/350/bmj.h1258

Tasian, G. E., & Ellison, J. S. (2021). The surgical improvement cycle: Improving surgical outcomes through partnerships and rigor. Journal of Urology. doi:10.1097/ju.0000000000001626

SLIDE DECK

Learning Session 7: Complex Interventions in Learning Health Systems