Adjunctive Therapies in Pediatric Severe Sepsis and Septic Shock: An Analysis through Multi-Center Linkage of the Virtual Pediatric Systems and PEDSnet
Pediatric severe sepsis, an overwhelming systemic inflammatory response to infection, is a leading cause of mortality in pediatric intensive care units (PICUs) worldwide. Despite decades of sepsis research, the main therapies available for the management of sepsis essentially remain goal-directed fluid resuscitation, timely antibiotic administration, and supportive care for organ dysfunction. Additional adjunctive therapies including […]