Active PEDSnet Studies

View active PEDSnet studies by grant funder:


RECOVER: Researching COVID to Enhance Recovery

Population Health in Children with Sex and Gender Differences

Diuretic and Inhaled Corticosteroid Treatment at US Children's Hospitals

Evaluation of the Gut-Kidney Axis in Kidney Stone Disease 

Medications and Weight Gain Across the Lifecourse in PCORnet

The ROUTT-B (Reduce Over-Utilized Tests and Treatments in Bronchiolitis) Study: Developing a Roadmap for De-Implementation

Pediatric Nephrology Center of Excellence

Privacy-preserving Methods and Tools for Handling Missing Data in Distributed Health Data Networks

Linking CTSA and IDDRC resources to support Down Syndrome DS-CONNECT 

Development of Brief Screening Algorithm for Early Identification of VWD in Women

Skeletal Outcomes in Children and Young Adults with Glomerular Disease


Feasibility of N-of-1 Trials in Children with Hypertension and Chronic Kidney Disease (NICHE-CKD) 

Identification of Systemic Lupus Erythematosus and Lupus Nephritisin a Multi-Institutional Pediatric Learning Health System

Comparative effectiveness of treatments for recurrent focal segmental glomerulosclerosis in pediatric kidney transplantation

Computable Phenotype for Polycystic Kidney Disease (PKD)

Treatment of Henoch-Schonlein purpura (HSP) Nephritis

Pilot Identification of Patients with Systemic Lupus Erythematosus (SLE) in the Pediatric Nephrology Data Resource

Membranoproliferative Glomerulonephritis (MPGN) in PEDSnet


Harnessing PCORnet to Study Comparative Effectiveness and Safety of Biologic Therapies

An Efficient Distributed Learning Framework for Integrating Evidence in Clinical Research Networks

Clinical Outcomes in Pediatric Patients with Overweight and Obesity Treated for Lower Respiratory Tract Disease

PEDSnet/SCILHS Healthy Weight Network Clinic Survey

Biologic Abatement and Capturing Kids’ Outcomes and Flare Frequency in Juvenile Spondyloarthritis (BACK-OFF JSpA)

Preserving Kidney Function in Children with Chronic Kidney Disease

Utilizing PCORnet to Reduce Gaps in Care and Improve Long-Term Outcomes in Adults with CHD

Comparative effectiveness of VNS versus continued pharmacologic treatment of Lennox-Gastaut Syndrome: reducing emergency seizure care and improving functional outcomes

Comparative Effectiveness of Surgery for Pediatric Kidney Stones Using a LHS

COVID-19 Healthcare Worker Exposure Response & Outcomes (HERO) Trial

HealthCore-Anthem Research Network (HCARN) 

The Economic Case for Eating Disorders Prevention and Early Detection: A Comparative Cost-Effectiveness Analysis of Six Intervention Strategies

Automating Quality and Safety Benchmarking for Children: Meeting the Needs of Health Systems and Patients

Anti-TNF Monotherapy versus Combination Therapy in Pediatric Crohn’s Disease

Statistical Methods for Phenotype Estimation and Analysis Using Electronic Health Records

Short-and Long-term Effects of Antibiotics on Childhood Growth

Comparative Effectiveness Bariatric Surgery

Automating Quality and Safety Benchmarking for Children: Meeting the Needs of Health Systems and Patients

Comparative Effectiveness of Surgery for Pediatric Kidney Stones Using a Learning Health System (PKIDS)

Characterizing Disease Trajectory for Improving Treatment in Pediatric Chrohn's Disease


Sentinel Initiative 

I-ACT Global Pediatric Clinical Trials Network

FDA BEST Initiative*

*Joint initiative with IBM


CDC BMI Trajectories Analysis in PEDSnet

Using EHR Data to Evaluate the Burden of Diabetes Mellitus in a National Network of Children’s Hospital Health Systems

COVID-19 Electronic Healthcare Data Initiative


Comparative Effectiveness of Alternative Approaches for Wound Closure

Outcomes of Pediatric Otitis Media with Effusion with and without Tympanostomy Tube Insertion

Developing Capacity to Conduct Proactive Post Marketing Safety Surveillance of Craniomaxillofacial Distractors Medical Device or Technology of Interest

Characterization and Utilization of Therapeutic Cardiac Devices in Children with Congenital Heart Disease

Structured interviews of Lived ExperiencE in Patients (SLEEP study) Obstructive Sleep Apnea and Central Sleep Apnea

Institutionally Funded

Creation of Computable Alopecia Areata Phenotype to Evaluate Epidemiology of Pediatric Alopecia Areata and Potential Health Care Disparities in care among children living with Alopecia Areata

COVID-Miner: Leveraging Artificial Intelligence to Facilitate Early Detection of Coronavirus Infection and Deterioration in the Pediatric Population

Effectiveness of Steroids and Croup in ICU

National Estimate for Sterile Injectable Chemotherapy Use for Pediatric Cancer Patients

Utilization of PEDSnet to create a novel classifier for children with nephrotic syndrome using aggregated clinical and genetic testing data 

Improving Pediatric Cancer Patients’ Nutritional Outcomes: A Multi-Institutional Approach Using Electronic Health Records

Adjunctive Therapies in Pediatric Severe Sepsis and Septic Shock: An Analysis through Multi-Center Linkage of the Virtual Pediatric Systems and PEDSnet

A Data-Driven Approach for Risk Stratification and Outcome Prediction for Pediatric Inflammatory Bowel Disease

SPARK Registry- PEDSnet Linkage Pilot

Growing National Rare Pediatric Brain Tumor Biobank Specimens From a National LHS


Learning Health Systems Mentored Career Development Program (K12)

AHRQ Child Health Quality Program (CHeQ)

Last updated 4/22/21