This study aims to expand understanding of how crystalloid fluid impacts sepsis survivors’ lives beyond 30 days.
Aim 1: Determine the most effective crystalloid fluid choice to
minimize sepsis-induced AKI and CKD in PRoMPT BOLUS trial participants
Aim 2: Measure the real-world impact of crystalloid fluid on sepsis-induced AKI and CKD
Funding Source:
Participating PEDSnet Sites:
- Cincinnati Children’s Hospital Medical Center
- Children’s Hospital of Philadelphia
- Children’s National Hospital
- Ann & Robert H. Lurie Children’s Hospital of Chicago
- Nationwide Children’s Hospital
- Seattle Children’s Hospital
- Nemours Children’s Health
- Texas Children’s Hospital
Study Investigator:
Vasoactive Selection in Pediatric Septic Shock and the Use of Cardiac Point-of-Care Ultrasound: A Retrospective Registry Analysis Across Multicenter Pediatric Emergency Medicine and Pediatric Critical Care
Pediatric septic shock requires rapid recognition of cardiovascular failure and timely treatment to restore adequate tissue perfusion. Vasoactive medications are central to management, yet considerable uncertainty remains regarding the optimal first‑line agent. Although guidelines recommend tailoring vasoactive choice to a…
Childhood Neighborhood Exposures and Pediatric Multiple Sclerosis
Question 1: How can we identify children with MS using ICD-10 codes in the PEDSnet dataset Question 2: How do neighborhood exposures influence the risk of pediatric MS development Aim 1: Validate a computable phenotype to identify pediatric MS. Aim…
Preventing Suicide among Sexual and Gender Diverse Youth
Suicide is the second leading cause of death among young adults in the United States. Sexual and gender diverse young adults (SGDYA) are at particularly high risk. SGDYA includes individuals who are lesbian, gay, bisexual, transgender, queer, or of another…