PEDSnet has published a total of 104 manuscripts.
Full list of PEDSnet Publications
2024
https://www.sciencedirect.com/science/article/pii/S0887899424000821
Multi-institutional assessment of otitis media epidemiology using real-world dataKavita Dedhia, Mitch Maltenfort, Lisa Elden, David Horn, Brianna Magnusen, Prasanth Pattisapu, Cedric V. Pritchett, Todd Wine, Levon Utidjian, Christopher B. Forrest, Multi-institutional assessment of otitis media epidemiology using real-world data, International Journal of Pediatric Otorhinolaryngology, 2024, 111921, ISSN 0165-5876, https://doi.org/10.1016/j.ijporl.2024.111921.
Moninder Kaur, Levon Utidjian, Nicholas S. Abend, Kimberley Dickinson, Robert Roebling, Jill McDonald, Mitchell G. Maltenfort, Nadia Foskett, Sami Elmoufti, Rejean M. Guerriero, Badal G. Jain, Nathan M. Pajor, Suchitra Rao, Renée A. Shellhaas, Laurel Slaughter, Christopher B. Forrest, Retrospective Multicenter Cohort Study on Safety and Electroencephalographic Response to Lacosamide for Neonatal Seizures, Pediatric Neurology, 2024,,ISSN 0887-8994, https://doi.org/10.1016/j.pediatrneurol.2024.03.007
Learning competing risks across multiple hospitals: one-shot distributed algorithms
Dazheng Zhang, Jiayi Tong, Naimin Jing, Yuchen Yang, Chongliang Luo, Yiwen Lu, Dimitri A Christakis, Diana Güthe, Mady Hornig, Kelly J Kelleher, Keith E Morse, Colin M Rogerson, Jasmin Divers, Raymond J Carroll, Christopher B Forrest, Yong Chen, Learning competing risks across multiple hospitals: one-shot distributed algorithms, Journal of the American Medical Informatics Association, 2024;, ocae027, https://doi.org/10.1093/jamia/ocae027
Postacute Sequelae of SARS-CoV-2 in Children
Suchitra Rao, Rachel S. Gross, Sindhu Mohandas, Cheryl R. Stein, Abigail Case, Benard Dreyer, Nathan M. Pajor, H. Timothy Bunnell, David Warburton, Elizabeth Berg, Jonathan B. Overdevest, Mark Gorelik, Joshua Milner, Sejal Saxena, Ravi Jhaveri, John C. Wood, Kyung E. Rhee, Rebecca Letts, Christine Maughan, Nick Guthe, Leah Castro-Baucom, Melissa S. Stockwell; Postacute Sequelae of SARS-CoV-2 in Children. Pediatrics 2024; e2023062570. 10.1542/peds.2023-062570
Chongliang Luo, Rui Duan, Mackenzie Edmondson, Jiasheng Shi, Mitchell Maltenfort, Jeffrey S. Morris, Christopher B. Forrest, Rebecca Hubbard, Yong Chen "Distributed proportional likelihood ratio model with application to data integration across clinical sites," The Annals of Applied Statistics, Ann. Appl. Stat. 18(1), 63-79, (March 2024)
Vaccine Effectiveness Against Long COVID in Children
Hanieh Razzaghi, Christopher B. Forrest, Kathryn Hirabayashi, Qiong Wu, Andrea Allen, Suchitra Rao, Yong Chen, H. Timothy Bunnell, Elizabeth A. Chrischilles, Lindsay G. Cowell, Mollie R. Cummins, David A. Hanauer, Miranda Higginbotham, Benjamin D. Horne, Carol R. Horowitz, Ravi Jhaveri, Susan Kim, Aaron Mishkin, Jennifer A. Muszynski, Susanna Naggie, Nathan M. Pajor, Anuradha Paranjape, Hayden T. Schwenk, Marion R. Sills, Yacob G. Tedla, David A. Williams, Charles Bailey; on behalf of the RECOVER Consortium, Vaccine Effectiveness Against Long COVID in Children. Pediatrics 2024; 10.1542/peds.2023-064446
Qiong Wu, Jiayi Tong, Bingyu Zhang, et al. Real-World Effectiveness of BNT162b2 Against Infection and Severe Diseases in Children and Adolescents. Ann Intern Med. [Epub 9 January 2024]. doi:10.7326/M23-1754
Pediatric Medical Subspecialist Use in Outpatient Settings
Forrest CB, Chen CP, Perrin EM, et al. Pediatric Medical Subspecialist Use in Outpatient Settings. JAMA Netw Open. 2024;7(1):e2350379. doi:10.1001/jamanetworkopen.2023.50379
2023
Assessing Alternative Approaches for Wound Closure in a National Pediatric Learning Health System
Lindsay A. Gil, Lindsey Asti, Leah Nishimura, Ashley R. Banks, Jennifer Woodard, Saleem Islam, Christopher B. Forrest, Shannon N. Acker, Loren Berman, Myron Allukian, Beth Rymeski, Sarah Greenberg, Kelly Kelleher, Peter C. Minneci, Assessing Alternative Approaches for Wound Closure in a National Pediatric Learning Health System, Journal of Surgical Research, Volume 295, 2024, Pages 783-790, ISSN 0022-4804, https://doi.org/10.1016/j.jss.2023.11.068.
Clinical Characteristics of US Adolescents Hospitalized for Eating Disorders 2010–2022
David I. Rappaport, Michael O’Connor, Cara Reedy, Megen Vo; Clinical Characteristics of US Adolescents Hospitalized for Eating Disorders 2010–2022. Hosp Pediatr January 2024; 14 (1): 52–58. https://doi.org/10.1542/hpeds.2023-007381
https://onlinelibrary.wiley.com/doi/10.1002/ajmg.a.63495
Huang, S. D., Bamba, V., Bothwell, S., Fechner, P. Y., Furniss, A., Ikomi, C., Nahata, L., Nokoff, N. J., Pyle, L., Seyoum, H., & Davis, S. M. (2023). Development and validation of a computable phenotype for Turner syndrome utilizing electronic health records from a national pediatric network. American Journal of Medical Genetics Part A, 1–11. https://doi.org/10.1002/ajmg.a.63495
Rao, S., Jing, N., Liu, X. et al. Spectrum of severity of multisystem inflammatory syndrome in children: an EHR-based cohort study from the RECOVER program. Sci Rep 13, 21005 (2023). https://doi.org/10.1038/s41598-023-47655-y
Derivation of paediatric blood pressure percentiles from electronic health records
Mitsnefes, M. M., Maltenfort, M., Denburg, M. R., Flynn, J. T., Schuchard, J., Dixon, B. B., Patel, H. P., Claes, D., Dickinson, K., Chen, Y., Gluck, C., Leonard, M., Verghese, P. S., & Forrest, C. B. (2023a). Derivation of paediatric blood pressure percentiles from electronic health records. eBioMedicine, 98, 104885. https://doi.org/10.1016/j.ebiom.2023.104885
Mental Health of Youth with Autism Spectrum Disorder and Gender Dysphoria
Nicole F. Kahn, Gina M. Sequeira, Valentino Reyes, Michelle M. Garrison, Felice Orlich, Dimitri A. Christakis, Tandy Aye, Lee Ann E. Conard, Nadia Dowshen, Anne E. Kazak, Leena Nahata, Natalie J. Nokoff, Raina V. Voss, Laura P. Richardson; Mental Health of Youth With Autism Spectrum Disorder and Gender Dysphoria. Pediatrics 2023; e2023063289. 10.1542/peds.2023-063289
Electronic health records identify timely trends in childhood mental health conditions
Elia, J., Pajer, K., Prasad, R. et al. Electronic health records identify timely trends in childhood mental health conditions. Child Adolesc Psychiatry Ment Health 17, 107 (2023). https://doi.org/10.1186/s13034-023-00650-7
Lorman V, Razzaghi H, Song X, Morse K, Utidjian L, et al. (2023) A machine learning-based phenotype for long COVID in children: An EHR-based study from the RECOVER program. PLOS ONE 18(8): e0289774. https://doi.org/10.1371/journal.pone.0289774
Co-occurring Autism Spectrum Disorder and Gender Dysphoria in Adolescents
Nicole F. Kahn, Gina M. Sequeira, Michelle M. Garrison, Felice Orlich, Dimitri A. Christakis, Tandy Aye, Lee Ann E. Conard, Nadia Dowshen, Anne E. Kazak, Leena Nahata, Natalie J. Nokoff, Raina V. Voss, Laura P. Richardson; Pediatrics 2023; e2023061363. 10.1542/peds.2023-061363
Ching, C.B., Dickinson, K., Karafilidis, J. et al. The real world experience of pediatric primary hyperoxaluria patients in the PEDSnet clinical research network. Eur J Pediatr (2023). https://doi.org/10.1007/s00431-023-05077-y
Clinical course and management of children with IgA vasculitis with nephritis
Stone, H.K., Mitsnefes, M., Dickinson, K. et al. Clinical course and management of children with IgA vasculitis with nephritis. Pediatric Nephrol (2023). https://doi.org/10.1007/s00467-023-06023-8
Safety of Intravenous Lacosamide in Hospitalized Children and Neonates
Fong SL, Utidjian L, Kaur M, Abend NS, Wainwright MS, Grande KM, Foskett N, Roebling R, Guerriero RM, Jain B, Rao S, Stoltenberg M, Williams P, Yuen N, Dickinson K, McDonald J, Maltenfort M, Forrest CB. Safety of Intravenous Lacosamide in Hospitalized Children and Neonates. Epilepsia. 2023 Jun 7. doi: 10.1111/epi.17676. Epub ahead of print. PMID: 37287398.
Coughlin JW, Nauman E, Wellman R, Coley RY, McTigue KM, Coleman KJ, Jones DB, Lewis KH, Tobin JN, Wee CC, Fitzpatrick SL, Desai JR, Murali S, Morrow EH, Rogers AM, Wood GC, Schlundt DG, Apovian CM, Duke MC, McClay JC, Soans R, Nemr R, Williams N, Courcoulas A, Holmes JH, Anau J, Toh S, Sturtevant JL, Horgan CE, Cook AJ, Arterburn DE; PCORnet Bariatric Study Collaborative. Preoperative Depression Status and 5 Year Metabolic and Bariatric Surgery Outcomes in the PCORnet Bariatric Study Cohort. Ann Surg. 2023 Apr 1;277(4):637-646. doi: 10.1097/SLA.0000000000005364. Epub 2022 Jan 19. PMID: 35058404; PMCID: PMC9994793.
Jhaveri R, Webb R, Razzaghi H, Schuchard J, Mejias A, Bennett TD, Jone PN, Thacker D, Schulert GS, Rogerson C, Cogen JD, Charles Bailey L, Forrest CB, Lee GM, Rao S; RECOVER consortium. Can Multisystem Inflammatory Syndrome in Children Be Managed in the Outpatient Setting? An EHR-Based Cohort Study From the RECOVER Program. J Pediatric Infect Dis Soc. 2023 Apr 18;12(3):159-162. doi: 10.1093/jpids/piac133. PMID: 36786218; PMCID: PMC10112676.
Tasian GE, Maltenfort MG, Rove K, Ching CB, Ramachandra P, DeFoor B, Fernandez N, Forrest CB, Ellison JS. Ureteral Stent Placement Prior to Definitive Stone Treatment Is Associated With Higher Postoperative Emergency Department Visits and Opioid Prescriptions for Youth Having Ureteroscopy or Shock Wave Lithotripsy. J Urol. 2023 Jun;209(6):1194-1201. doi: 10.1097/JU.0000000000003389. Epub 2023 Feb 22. PMID: 36812398.
Yizhao Zhou, Jiasheng Shi, Ronen Stein, Xiaokang Liu, Robert N Baldassano, Christopher B Forrest, Yong Chen, Jing Huang, Missing data matter: an empirical evaluation of the impacts of missing EHR data in comparative effectiveness research, Journal of the American Medical Informatics Association, 2023;, ocad066, https://doi.org/10.1093/jamia/ocad066
Vitaly Lorman, PhD, Suchitra Rao, MBBS, MSCS, Ravi Jhaveri, MD, Abigail Case, MD, Asuncion Mejias, MD, PhD, MsCS, Nathan M Pajor, MD, MS, Payal Patel, MD, Deepika Thacker, Md, Seuli Bose-Brill, MD, Jason Block, MD, MPH, Patrick C Hanley, MD, MSHQS, Priya Prahalad, MD, PhD, Yong Chen, PhD, Christopher B Forrest, MD, PhD, L Charles Bailey, MD, PhD, Grace M Lee, MD, MPH, Hanieh Razzaghi, MPH, Understanding pediatric long COVID using a tree-based scan statistic approach: An EHR-based cohort study from the RECOVER Program, JAMIA Open, 2023;, ooad016,
Sandra Amaral, Julia Schuchard, Donna Claes, Allison Dart, Larry A. Greenbaum, Susan F. Massengill, Meredith A. Atkinson, Joseph T. Flynn, Vikas R. Dharnidharka, Sahar Fathallah-Shaykh, Ora Yadin, Zubin J. Modi, Amira Al-Uzri, Amy C. Wilson, Katherine M. Dell, Hiren P. Patel, Cortney Bruno, Bradley Warady, Susan Furth, Christopher B. Forrest, Patient-Reported Outcomes Over 24 Months in Pediatric CKD: Findings From the MyKidneyHealth Cohort Study, American Journal of Kidney Diseases, 2023, ISSN 0272-6386, https://doi.org/10.1053/j.ajkd.2022.12.014.
Asuncion Mejias, Julia Schuchard, Suchitra Rao, Tellen D. Bennett, Ravi Jhaveri, Deepika Thacker, L. Charles Bailey, Dimitri A. Christakis, Nathan M. Pajor, Hanieh Razzaghi, Christopher B. Forrest, Grace M. Lee, Leveraging serologic testing to identify children at risk for post-acute sequelae of SARS-CoV-2 infection: An EHR-based cohort study from the RECOVER program, The Journal of Pediatrics, 2023, ISSN 0022-3476, https://doi.org/10.1016/j.jpeds.2023.02.005.
https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-022-07038-6#citeas
https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-022-07038-6#citeas
Weiss, P.F., Sears, C.E., Brandon, T.G. et. al. Biologic Abatement and Capturing Kids’ Outcomes and Flare Frequency in Juvenile Spondyloarthritis (BACK-OFF JSpA): study protocol for a randomized pragmatic trial. Trials 24, 100 (2023). https://doi.org/10.1186/s13063-022-07038-6
Gluck, Caroline A.1; Forrest, Christopher B.2,3; Davies, Amy Goodwin3; Maltenfort, Mitchell3; Mcdonald, Jill R.3; Mitsnefes, Mark4; Dharnidharka, Vikas R.5; Dixon, Bradley P.6; Flynn, Joseph T.7; Somers, Michael J.8; Smoyer, William E.9; Neu, Alicia10; Hovinga, Collin A.11; Skversky, Amy L.12; Eissing, Thomas12; Kaiser, Andreas12; Breitenstein, Stefanie12; Furth, Susan L.2,13,14; Denburg, Michelle R.2,13,14. Evaluating Kidney Function Decline in Children with Chronic Kidney Disease Using a Multi-Institutional Electronic Health Record Database. Clinical Journal of the American Society of Nephrology ():10.2215/CJN.0000000000000051, January 17, 2023. | DOI: 10.2215/CJN.0000000000000051
2022
Kiernan D, Carton T, Toh S, Phua J, Zirkle M, Louzao D, Haynes K, Weiner M, Angulo F, Bailey C, Bian J, Fort D, Grannis S, Krishnamurthy AK, Nair V, Rivera P, Silverstein J, Marsolo K. Establishing a framework for privacy-preserving record linkage among electronic health record and administrative claims databases within PCORnet®, the National Patient-Centered Clinical Research Network. BMC Res Notes. 2022 Oct 31;15(1):337. doi: 10.1186/s13104-022-06243-5. PMID: 36316778; PMCID: PMC9620597.
Xiaokang Liu, Jessica Chubak, Rebecca A Hubbard, Yong Chen, SAT: a Surrogate-Assisted Two-wave case boosting sampling method, with application to EHR-based association studies, Journal of the American Medical Informatics Association, Volume 29, Issue 5, May 2022, Pages 918–927, https://doi.org/10.1093/jamia/ocab267
https://doi.org/10.1093/jamiaopen/ooad016
ODACH: a one-shot distributed algorithm for Cox model with heterogeneous multi-center data
Luo, C., Duan, R., Naj, A.C. et al. ODACH: a one-shot distributed algorithm for Cox model with heterogeneous multi-center data. Sci Rep 12, 6627 (2022). https://doi.org/10.1038/s41598-022-09069-0
https://academic.oup.com/jamia/article/29/8/1366/6586580
Chongliang Luo, Md Nazmul Islam, Natalie E Sheils, John Buresh, Martijn J Schuemie, Jalpa A Doshi, Rachel M Werner, David A Asch, Yong Chen, dPQL: a lossless distributed algorithm for generalized linear mixed model with application to privacy-preserving hospital profiling, Journal of the American Medical Informatics Association, Volume 29, Issue 8, August 2022, Pages 1366–1371, https://doi.org/10.1093/jamia/ocac067
Liu X, Duan R, Luo C, Ogdie A, Moore JH, Kranzler HR, Bian J, Chen Y. Multisite learning of high-dimensional heterogeneous data with applications to opioid use disorder study of 15,000 patients across 5 clinical sites. Sci Rep. 2022 Jun 30;12(1):11073. doi: 10.1038/s41598-022-14029-9. PMID: 35773438; PMCID: PMC9245877.
Experiences of U.S. Nurses Compared With Nonnurses in the First Year of COVID-19
Chen-Lim, Mei Lin; McCabe, Margaret A.; Xu, Haolin; Thomas, Laine E.; Forrest, Christopher B.; Birnbaum, Shira; Webb, Laura E.; O’Brien, Emily C.. Experiences of U.S. Nurses Compared With Nonnurses in the First Year of COVID-19: Findings From a National Registry. Nursing Research: 11/12 2022 - Volume 71 - Issue 6 - p 421-431 doi: 10.1097/NNR.0000000000000610
Hepatic Abnormalities in Youth With Turner Syndrome
Singh I, Noel G, Barker JM, Chatfield KC, Furniss A, Khanna AD, Nokoff NJ, Patel S, Pyle L, Nahata L, Cole FS, Ikomi C, Bamba V, Fechner PY, Davis SM. Hepatic abnormalities in youth with Turner syndrome. Liver Int. 2022 Oct;42(10):2237-2246. doi: 10.1111/liv.15358. Epub 2022 Jul 16. PMID: 35785515; PMCID: PMC9798872.
Rao S, Lee GM, Razzaghi H, Lorman V, Mejias A, Pajor NM, Thacker D, Webb R, Dickinson K, Bailey LC, Jhaveri R, Christakis DA, Bennett TD, Chen Y, Forrest CB. Clinical Features and Burden of Postacute Sequelae of SARS-CoV-2 Infection in Children and Adolescents. JAMA Pediatr. 2022 Oct 1;176(10):1000-1009. doi: 10.1001/jamapediatrics.2022.2800. PMID: 35994282; PMCID: PMC9396470.
Coleman KJ, Wellman R, Fitzpatrick SL, Conroy MB, Hlavin C, Lewis KH, Coley RY, McTigue KM, Tobin JN, McBride CL, Desai JR, Clark JM, Toh S, Sturtevant JL, Horgan CE, Duke MC, Williams N, Anau J, Horberg MA, Michalsky MP, Cook AJ, Arterburn DE, Apovian CM; PCORnet Bariatric Study Collaborative. Comparative Safety and Effectiveness of Roux-en-Y Gastric Bypass and Sleeve Gastrectomy for Weight Loss and Type 2 Diabetes Across Race and Ethnicity in the PCORnet Bariatric Study Cohort. JAMA Surg. 2022 Oct 1;157(10):897-906. doi: 10.1001/jamasurg.2022.3714. PMID: 36044239; PMCID: PMC9434478.
Addison, Jessica MD, MS*; Razzaghi, Hanieh MPH†,‡; Bailey, Charles MD, PhD†,‡; Dickinson, Kimberley BS†,‡; Corathers, Sarah D. MD§,; Hartley, David M. PhD, MPH,∥; Utidjian, Levon MD†,‡; Carle, Adam C. PhD, MA¶∥,**; Rhodes, Erinn T. MD, MPH††,‡‡; Alonso, G. Todd MD§§; Haller, Michael J. MD; Gannon, Anthony W. MD, MSCE∥∥; Indyk, Justin A. MD, MBI***,†††; Arbeláez, Ana Maria MD, MSCL‡‡‡,§§§; Shenkman, Elizabeth PhD; Forrest, Christopher B. MD, PhD†; Eckrich, Daniel MLIS∥∥; Magnusen, Brianna MD‡‡‡; Davies, Sara Deakyne MPH§§; Walsh, Kathleen E. MD, MS‡‡,∥∥∥. Testing an Automated Approach to Identify Variation in Outcomes among Children with Type 1 Diabetes across Multiple Sites. Pediatric Quality and Safety 7(5):p e602, September/October 2022. | DOI: 10.1097/pq9.0000000000000602
Cardiac Complications After SARS-CoV-2 Infection and mRNA COVID-19 Vaccination
Block JP, Boehmer TK, Forrest CB, Carton TW, Lee GM, Ajani UA, Christakis DA, Cowell LG, Draper C, Ghildayal N, Harris AM, Kappelman MD, Ko JY, Mayer KH, Nagavedu K, Oster ME, Paranjape A, Puro J, Ritchey MD, Shay DK, Thacker D, Gundlapalli AV. Cardiac Complications After SARS-CoV-2 Infection and mRNA COVID-19 Vaccination - PCORnet, United States, January 2021-January 2022. MMWR Morb Mortal Wkly Rep. 2022 Apr 8;71(14):517-523. doi: 10.15585/mmwr.mm7114e1. PMID: 35389977; PMCID: PMC8989373.
McKenzie PL, Maltenfort M, Bruckner AL, Gupta D, Harfmann KL, Hyde P, Forrest CB, Castelo-Soccio L. Evaluation of the Prevalence and Incidence of Pediatric Alopecia Areata Using Electronic Health Record Data. JAMA Dermatol. 2022 Apr 6:e220351. doi: 10.1001/jamadermatol.2022.0351. Epub ahead of print. PMID: 35385065; PMCID: PMC8988018.
Ellison JS, Lorenzo M, Beck H, Beck R, Chu DI, Forrest C, Huang J, Kratchman A, Kurth A, Kurth L, Kurtz M, Lendvay T, Sturm R, Tasian G; Pediatric KIDney Stone Care Improvement Network. Comparative effectiveness of paediatric kidney stone surgery (the PKIDS trial): study protocol for a patient-centred pragmatic clinical trial. BMJ Open. 2022 Apr 5;12(4):e056789. doi: 10.1136/bmjopen-2021-056789. PMID: 35383073; PMCID: PMC8983998.
Severity of Acute COVID-19 in Children <18 Years Old March 2020 to December 2021
Forrest CB, Burrows EK, Mejias A, Razzaghi H, Christakis D, Jhaveri R, Lee GM, Pajor NM, Rao S, Thacker D, Bailey LC. Severity of Acute COVID-19 in Children <18 Years Old March 2020 to December 2021. Pediatrics. 2022 Apr 1;149(4):e2021055765. doi: 10.1542/peds.2021-055765. PMID: 35322270.
Lusk JB, Xu H, Thomas LE, Cohen LW, Hernandez AF, Forrest CB, Michtalik HJ, Turner KB, O'Brien EC, Barrett NJ; HERO Research Program. Racial/Ethnic Disparities in Healthcare Worker Experiences During the COVID-19 Pandemic: An Analysis of the HERO Registry. EClinicalMedicine. 2022 Mar 5;45:101314. doi: 10.1016/j.eclinm.2022.101314. PMID: 35265822; PMCID: PMC8898082.
Measuring BMI change among children and adolescents
Freedman DS, Goodwin Davies AJ, Phan TT, Cole FS, Pajor N, Rao S, Eneli I, Kompaniyets L, Lange SJ, Christakis DA, Forrest CB. Measuring BMI change among children and adolescents. Pediatr Obes. 2022 Jun;17(6):e12889. doi: 10.1111/ijpo.12889. Epub 2022 Jan 22. PMID: 35064761.
Antibiotics prior to age 2 years have limited association with preschool growth trajectory
Bailey LC, Bryan M, Maltenfort M, Block JP, Teneralli R, Lunsford D, Boone-Heinonen J, Eneli I, Horgan CE, Lin PD, Reynolds JS, Solomonides AE, Janicke D, Sturtevant JL, Toh S, Taveras E, Appelhans BM, Arterburn D, Daley MF, Dempsey A, Dugas LR, Finkelstein J, Fitzpatrick SL, Goodman A, Gurka MJ, Heerman WJ, Horberg M, Hossain MJ, Hsia DS, Isasi CR, Kharbanda EO, Messito MJ, Murphy K, O'Bryan K, Peay HL, Prochaska MT, Puro J, Rayas M, Rosenman MB, Taylor B, VanWormer JJ, Willis Z, Yeramaneni S, Forrest CB; PCORnet Antibiotics and Childhood Growth Study Group. Antibiotics prior to age 2 years have limited association with preschool growth trajectory. Int J Obes (Lond). 2022 Apr;46(4):843-850. doi: 10.1038/s41366-021-01023-w. Epub 2022 Jan 8. PMID: 34999718; PMCID: PMC8967797.
Freedman DS, Goodwin-Davies AJ, Kompaniyets L, Lange SJ, Goodman AB, Phan TT, Rao S, Eneli I, Forrest CB. Interrelationships among age at adiposity rebound, BMI during childhood, and BMI after age 14 years in an electronic health record database. Obesity (Silver Spring). 2022 Jan;30(1):201-208. doi: 10.1002/oby.23315. PMID: 34932881.
2021
Wenderfer SE, Chang JC, Goodwin Davies A, Luna IY, Scobell R, Sears C, Magella B, Mitsnefes M, Stotter BR, Dharnidharka VR, Nowicki KD, Dixon BP, Kelton M, Flynn JT, Gluck C, Kallash M, Smoyer WE, Knight A, Sule S, Razzaghi H, Bailey LC, Furth SL, Forrest CB, Denburg MR, Atkinson MA. Using a Multi-Institutional Pediatric Learning Health System to Identify Systemic Lupus Erythematosus and Lupus Nephritis: Development and Validation of Computable Phenotypes. Clin J Am Soc Nephrol. 2022 Jan;17(1):65-74. doi: 10.2215/CJN.07810621.
Behavioral Health Diagnoses in Youth with Gender Dysphoria Compared with Controls: A PEDSnet study
Nunes-Moreno M, Buchanan C, Cole FS, Davis S, Dempsey A, Dowshen N, Furniss A, Kazak AE, Kerlek AJ, Margolis P, Pyle L, Razzaghi H, Reirden DH, Schwartz B, Sequeira GM, Nokoff NJ. Behavioral Health Diagnoses in Youth with Gender Dysphoria Compared with Controls: A PEDSnet Study. J Pediatr. 2022 Feb;241:147-153.e1. doi: 10.1016/j.jpeds.2021.09.032.
Developing a Systemic Approach to Data Quality Assessment Based on Intended Use of Clinical Data
Razzaghi H, Greenberg J, Bailey LC. Developing a systematic approach to assessing data quality in secondary use of clinical data based on intended use. Learn Health Syst. 2021 May 3;6(1):e10264. doi: 10.1002/lrh2.10264.
Early Life Antibiotic Prescriptions and Weight Outcomes in Children 10 Years of Age
Rifas-Shiman SL, Bailey LC, Lunsford D, et al. PCORnet Antibiotics and Childhood Growth Study Group. Early Life Antibiotic Prescriptions and Weight Outcomes in Children 10 Years of Age. Acad Pediatr. 2021 Mar;21(2):297-303. doi: 10.1016/j.acap.2020.10.016
Forrest CB, Xu H, Thomas LE, et al. Impact of the Early Phase of the COVID-19 Pandemic on US Healthcare Workers: Results from the HERO Registry. Journal of General Internal Medicine. 2021. doi:10.1007/s11606-020-06529-z
A Longitudinal Comparison of Alternatives to CDC BMI Z-Scores for Children With Very High BMIs
Freedman DS, Goodwin Davies AJ, Kompaniyets L, et al. A Longitudinal Comparison of Alternatives to CDC BMI Z-Scores for Children With Very High BMIs. J Pediatr. 2021 Mar 4:S0022-3476(21)00211-0. doi: 10.1016/j.jpeds.2021.02.072
Applied Methods for Estimating Transition Probabilities from Electronic Health Record Data
Rodriguez PJ, Ward ZJ, Long MW, Austin SB, Wright DR. Applied Methods for Estimating Transition Probabilities from Electronic Health Record Data. Medical Decision Making. 2021;41(2):143-152. doi:10.1177/0272989x20985752
Provider Specialty and Receipt of Metabolic Monitoring for Children Taking Antipsychotics
Shenkman E, Thompson L, Bussing R, et al. Provider Specialty and Receipt of Metabolic Monitoring for Children Taking Antipsychotics. Pediatrics. 2020;147(1). doi:10.1542/peds.2020-0658
PCORnet® 2020: current state, accomplishments, and future directions
Forrest CB, McTigue KM, Hernandez AF, et al. PCORnet® 2020: current state, accomplishments, and future directions. J Clin Epidemiol. 2021 Jan;129:60-67. doi: 10.1016/j.jclinepi.2020.09.036
2020
Bailey LC, Razzaghi H, Burrows EK, et al. Assessment of 135 794 Pediatric Patients Tested for Severe Acute Respiratory Syndrome Coronavirus 2 Across the United States. JAMA Pediatr. Published online November 23, 2020. doi:10.1001/jamapediatrics.2020.5052
Khare R, Kappelman MD, Samson C, Pyrzanowski J, Darwar RA, Forrest CB, Bailey CC, Margolis P, Dempsey A, And the PEDSnet Computable Phenotype Working Group. Development and Evaluation of an EHR-Based Computable Phenotype for Identification of Pediatric Crohn's Disease Patients in a National Pediatric Learning Health System. Learning Health Systems Journal, 2020; e10243.
Learning from local to global: An efficient distributed algorithm for modeling time-to-event data
Duan R, Luo C, Schuemie MJ, et al. Learning from local to global: An efficient distributed algorithm for modeling time-to-event data. J Am Med Inform Assoc. 2020 Jul 1;27(7):1028-1036. doi: 10.1093/jamia/ocaa044
Duan R, Boland MR, Liu Z, Liu Y, Chang HH, Xu H, Chu H, Schmid CH, Forrest CB, Holmes JH, Schuemie MJ, Berlin JA, Moore JH, Chen Y. Learning from Electronic Health Records Across Multiple Sites: A Communication-Efficient and Privacy-Preserving Distributed Algorithm. Journal of the American Medical Informatics Association, 2020; 27(3): 376-385. https://doi.org/10.1093/jamia/ocz199.
2019
Using Electronic Health Record Data to Rapidly Identify Children with Glomerular Disease for Clinical Research
Denburg MR, Razzaghi H, Bailey LC, Sorrano DE, Pollack AH, Dharnidharka VR, Mitsnefes MM, Smoyer WE, Somers MJG, Zaritsky JJ, Flynn JT, Claes DJ, Dixon BP, Benton M, Mariani LH, Forrest CB, Furth SL. Using Electronic Health Record Data to Rapidly Identify Children with Glomerular Disease for Clinical Research. Journal of the American Society of Nephrology, 2019. https://doi.org/10.1681/ASN.2019040365
Estimation of Eating Disorders Prevalence by Age and Associations with Mortality in a Simulated Nationally Representative US Cohort
Ward ZJ, Rodriguez P, Wright DR, Austin B, Long MW. Estimation of Eating Disorders Prevalence by Age and Associations with Mortality in a Simulated Nationally Representative US Cohort. JAMA Network Open, 2019; 2(10)e1912925. doi: 10.1001/jamanetworkopen.2019.12925.
Privacy-Protecting Multivariable-Adjusted Distributed Regression Analysis for Multi-Center Pediatric Study
Toh S, Rifas-Shiman SL, Lin PD, Bailey LC, Forrest CB, Horgan CE, Lunsford D, Moyneur E, Sturtevant JL, Young JG, Block JP, PCORnet Antibiotics and Childhood Growth Study Group. Privacy-Protecting Multivariable-Adjusted Distributed Regression Analysis for Multi-Center Pediatric Study. Ped Research, 2019. doi: 10.1038/s41390-019-0596-0.
Effects of Age, Sex, Race/Ethnicity, and Allergy Status in Obesity-Related Pediatric Asthma
Lang JE, Bunnell HT, Lima JJ, Hossain MDJ, Wysocki T, Bacharier L, Dempsey A, Ulrich L, Test MR, Forrest CB. Effects of Age, Sex, Race/Ethnicity, and Allergy Status in Obesity-Related Pediatric Asthma. Pediatric Pulmonology, 2019. https://doi.org/10.1002/ppul.24470
Strengthening the Evidence Base for Pediatric Medical Devices Using Real-World Data
Fleurance, RL, Forrest CB, Shuren J. Strengthening the Evidence Base for Pediatric Medical Devices Using Real-World Data. Journal of Pediatrics, 2019. doi.org/10.1016/j.jpeds.2019.06.060
Design and Refinement of a Data Quality Assessment Workflow for a Large Pediatric Research Network
Khare R, Utidjian L, Razzaghi H et al. Design and Refinement of a Data
Quality Assessment Workflow for a Large Pediatric Research Network. eGEMs (Generating Evidence & Methods to improve patient outcomes). 2019;7(1):36. doi:10.5334/egems.294
Development and Evaluation of a Computable Phenotype to Identify Pediatric Leukemia and Lymphoma Patients Treated with Chemotherapy using Electronic Health Record Data
Phillips CA, Razzaghi H, Aglio T, McNeil MJ, Salvensen-Quinn M, Sopfe J, Wilkes JJ, Forrest CB, Bailey LC. (2019). Development and Evaluation of a Computable Phenotype to Identify Pediatric Leukemia and Lymphoma Patients Treated with Chemotherapy using Electronic Health Record Data. Pediatric Blood and Cancer, 2019; 66:e27876.
Use of EHR-Based Pediatric Quality Measures
Hartley,
D, Jonas, S, Grossoehme, D, Kelly, A, Dodds, C, Alford, S,
Shenkman, E, Simmons, J, Bailey, L, Razzaghi, H, Utidjian, L,
McCafferty-Fernandez, J, Cole, F, Smallwood, J, Werk, L and Walsh,
K. Use of EHR-Based Pediatric Quality Measures: Views of Health
System Leaders and Parents. American Journal of Medical Quality, 2019. p.106286061985032.
Developing Pediatric
Patient Safety Research Priorities
Miller M, Mistry
K. Developing Pediatric Patient Safety Research Priorities. Pediatrics, 2019; 143(2), p.e20182970.
Priorities for
Pediatric Patient Safety Research
Hoffman J,
Keeling N, Forrest C, Tubbs-Cooley H, Moore E, Oehler E, Wilson S, Schainker E,
Walsh K. Priorities for Pediatric Patient Safety Research. Pediatrics, 2018; 143(2), p.e20180496.
Maternal Antibiotic Use During Pregnancy and Childhood Obesity at Age 5 Years
Herman W, Daley M, Boone-Heinonen J, Rifas-Shiman S, Bailey L, Forrest CB, Young J,
Gillman M, Horgan C, Janicke D, Jenter C, Kharbanda E, Lunford D, Messito M,
Toh S, Block J. Maternal Antibiotic Use During Pregnancy and Childhood Obesity
at Age 5 Years. International Journal of Obesity, 2018.
2018
Learning Health Systems
Deans K, Sabihi S, Forrest C. Learning Health Systems. U.S. National Library of Medicine, 2018.
Block J, Bailey L, Gillman M, Lunsford D, Daley, M, Eneli I, Finkelstein J, Heerman W, Horgan C, Hsia D, Jay M, Rao G, Reynolds J, Rifas-Shiman S, Sturtevant J, Toh S, Trasande L, Young J and Forrest C. Early Antibiotic Exposure and Weight Outcomes in Young Children. Pediatrics, 2018; 142(6), p.e20180290.
Comparative
Effectiveness of Bariatric Procedures Among Adolescents: the PCORnet Bariatric
Study
Inge T, Coley R, Bazzano L, Xanthakos S, McTigue K, Arterburn D, Williams N, Wellman
R, Coleman K, Courcoulas A, Desai N, Anau J, Pardee R, Toh S, Janning C, Cook A,
Sturtevant J, Horgan C, Zebrick A, Michalsky M and P. C. B. S. Collaborative. Comparative
Effectiveness of Bariatric Procedures Among Adolescents: The PCORnet Bariatric Study.
Surgery for Obesity and Relaedt Diseases,
2018; 14(9): 1374-1386.
A
Bayesian Latent Class Approach for EHR-based Phenotyping
Hubbard R, Huang J, Harton J, Oganisian A, Choi G, Utidjian L, Eneli I, Bailey
L and Chen Y. A Bayesian Latent Class Approach for EHR-based Phenotyping. Stat Med, 2018; 38(1): 74-87.
Comparative
Effectiveness and Safety of Bariatric Procedures for Weight Loss: A PCORnet
Cohort Study
Arterburn D, Wellman R, Emiliano A, Smith S, Odegaard A, Murali S, Williams N,
Coleman K, Courcoulas A, Coley R, Anau J, Pardee R, Toh S, Janning C, Cook A,
Sturtevant J, Horgan C, McTigue K and P. C. B. S. Collaborative. Comparative
Effectiveness and Safety of Bariatric Procedures for Weight Loss: A PCORnet
Cohort Study. Ann Intern Med, 2018;
169(11): 741-750.
Developing
a Framework for the Ethical Design and Conduct of Pragmatic Trials in
Healthcare: a Mixed Methods Research Protocol
Taljaard M, Weijer C, Grimshaw J, Ali A, Brehaut J, Campbell M, Carroll K,
Edwards S, Eldridge S, Forrest C, Giraudeau B, Goldstein C, Graham I, Hemming K,
Hey S, Horn A, Jairath V, Klassen T, London A, Marlin S, Marshall J, McIntyre L,
McKenzie J, Nicholls S, Paprica P, Zwarenstein M and Fergusson D. Developing a Framework
for the Ethical Design and Conduct of Pragmatic Trials in Healthcare: A Mixed Methods
Research Protocol." Trials,
2018;19(1): 525.
Being
Overweight or Obese and the Development of Asthma
Lang J, Bunnell T, Hossain M, Wysocki T, Lima J, Finkel H, Bacharier L, Dempsey
A, Sarzynsk L, Test M, Forrest C. Being Overweight or Obese and the Development
of Asthma. Pediatrics, 2018; 142(6). doi:
10.1542/peds.2018-2119.
Methods
for Examining Data Quality in Healthcare Integrated Data Repositories
Huser V, Kahn M, Brown J and Gouripeddi R. Methods for Examining Data Quality
in Healthcare Integrated Data Repositories. Pac
Symp Biocomput, 2018; 23: 628-633.
Predicting
Causes of Data Quality Issues in a Clinical Data Research Network
Khare R, Ruth B, Miller M, Tucker J, Utidjian L, Razzaghi H, Patibandla N,
Burrows E and Bailey L. Predicting Causes of Data Quality Issues in a Clinical
Data Research Network. AMIA Jt Summits
Transl Sci Proc, 2018; 2017: 113-121.
From
Strangers in a Foreign Land to Active, Engaged Citizens
Scharpen A and Stille C. From Strangers in a Foreign Land to Active, Engaged
Citizens. Pediatrics, 2018;
141(2).
PCORnet
Antibiotics and Childhood Growth Study: Process for Cohort Creation and Cohort
Description
Block J, Bailey L, Gillman M, Lunsford D, Boone-Heinonen J, Cleveland L,
Finkelstein J, Horgan C, Jay M, Reynolds J, Sturtevant J, Forrest C and P. C.
A. C. G. S. Group. PCORnet Antibiotics and Childhood Growth Study: Process for
Cohort Creation and Cohort Description. Acad
Pediatr, 2018; 18(5): 569-576.
Retrospective
Analysis of Candida-related Conditions in Infancy and Early Childhood Caries
Jean J, Goldberg S, Khare R, Bailey L, Forrest C, Hajishengallis E and Koo H.
Retrospective Analysis of Candida-related Conditions in Infancy and Early
Childhood Caries. Pediatr Dent, 2018;
40(2), 131-135.
PCORnet's
Collaborative Research Groups
Pletcher M, Forrest C and Carton T. PCORnet's Collaborative Research Groups. Patient Related Outcome Measures, 2018; 9,
91-95. doi: 10.2147/PROM.S141630
Large
Databases for Pediatric Research on Children with Autism Spectrum Disorder
Kuhlthau KA, Bailey LC, Baer BL, Coury DL, Law JK, Murray DS, Razzaghi H, Forrest CB, Lipkin PH. PCORnet Large Databases for Pediatric Research on Children with Autism Spectrum Disorder. J Dev Behav Pediatr, 2018; 39(2): 168-176.
2017
The
National Patient-Centered Clinical Research Network (PCORnet) Bariatric Study
Cohort: Rationale, Methods, and Baseline Characteristics
Toh S, Rasmussen-Torvik LJ, Harmata EE, Pardee R, Saizan R, Malanga E, Sturtevant JL, Horgan CE, Anau J, Janning CD, Wellman RD, Coley RY, Cook AJ, Courcoulas AP, Coleman KJ, Williams NA, McTigue KM, Arterburn D, McClay J, PCORnet Bariatric Surgery Collaborative. The National Patient-Centered Clinical Research Network (PCORnet) Bariatric Study Cohort: Rationale, Methods, and Baseline Characteristics. JMIR Research Protocols, 2017; 6(12): e222.
Development
of the Learning Health System Researcher Core Competencies
Forrest C, Chesley F Jr, Tregear M and Mistry K. Development of the Learning
Health System Researcher Core Competencies. Health
Serv Res, 2017.
Applying
Evidence From Clinical Trials: Need for Pediatric Learning Health System
Research
Mistry K and Forrest C. Applying Evidence From Clinical Trials: Need for
Pediatric Learning Health System Research. Pediatrics,
2017; 140(6).
A
Comparison of Data Quality Assessment Checks in Six Data Sharing Networks
Callahan T, Bauck A, Bertoch D, Brown J, Khare R, Ryan P, Staab J, Zozus M and Kahn
M. A Comparison of Data Quality Assessment Checks in Six Data Sharing Networks.
EGEMS (Wash DC), 2017; 5(1): 8.
A
Longitudinal Analysis of Data Quality in a Large Pediatric Data Research
Network
Khare R, Utidjian L, Ruth B, Kahn M, Burrows E, Marsolo K, Patibandla N,
Razzaghi H, Colvin R, Ranade D, Kitzmiller M, Eckrich D and Bailey C. A Longitudinal
Analysis of Data Quality in a Large Pediatric Data Research Network. J Am Med Inform Assoc, 2017; 24(6):
1072-1079.
Antibiotics,
Infections, and Childhood Obesity
Forrest C, Block J and Bailey L. Antibiotics, Infections, and Childhood Obesity.
Lancet Diabetes Endocrinol, 2017;
5(1), 2-3.
2016
Building
Learning Health Systems to Accelerate Research and Improve Outcomes of Clinical
Care in Low- and Middle-Income Countries
English M, Irimu G, Agweyu A, Gathara D, Oliwa J, Ayieko P, Were F, Paton C,
Tunis S and Forrest C. Building Learning Health Systems to Accelerate Research
and Improve Outcomes of Clinical Care in Low- and Middle-Income Countries. PLoS Med, 2016; 13(4): e1001991.
Report
of the National Heart, Lung, and Blood Institute Working Group: An Integrated
Network for Congenital Heart Disease Research
Pasquali S, Jacobs J, Farber G, Bertoch D, Blume E, Burns K, Campbell R, Chang
A, Chung W, Riehle-Colarusso T, Curtis L, Forrest C, Gaynor W, Gaies M, Go A,
Henchey P, Martin G, Pearson G, Pemberton V, Schwartz S, Vincent R and Kaltman
J. Report of the National Heart, Lung, and Blood Institute Working Group: An
Integrated Network for Congenital Heart Disease Research. Circulation, 2016; 133(14): 1410-1418.
Learning
Health Systems as Facilitators of Precision Medicine
Ramsey L, Mizuno T, Vinks A and Margolis P. Learning Health Systems as Facilitators
of Precision Medicine. Clin Pharmacol
Ther, 2016; 101(3), 359-367.
2014
Addressing
Electronic Clinical Information in the Construction of Quality Measures
Bailey L, Mistry K, Tinoco A, Earls M, Rallins M, Hanley K, Christensen K,
Jones M and Woods D. Addressing electronic clinical information in the
construction of quality measures. Acad
Pediatr, 2014; 14(5 Suppl): S82-89.
Building
a Common Pediatric Research Terminology for Accelerating Child Health Research
Kahn M, Bailey L, Forrest C, Padula M and Hirschfeld S. Building a common
pediatric research terminology for accelerating child health research. Pediatrics, 2014; 133(3), 516-525.
PEDSnet:
a National Pediatric Learning Health System
Forrest C, Margolis P, Bailey L, Marsolo K, Del Beccaro M, Finkelstein J, Milov
D, Vieland V, Wolf B, Yu F and Kahn M. PEDSnet: a National Pediatric Learning
Health System. J Am Med Inform Assoc,
2014; 21(4): 602-606.
PEDSnet:
How a Prototype Pediatric Learning Health System is Being Expanded into a
National Network
Forrest C, Margolis P, Seid M and Colletti R. PEDSnet: how a prototype
pediatric learning health system is being expanded into a national network. Health Aff (Millwood), 2014; 33(7),
1171-1177. doi: 10.1377/hlthaff.2014.0127
2013
Multi-Institutional
Sharing of Electronic Health Record Data to Assess Childhood Obesity
Bailey L, Milov D, Kelleher K, Kahn M, Del Beccaro M, Yu F, Richards T and
Forrest C. Multi-Institutional Sharing of Electronic Health Record Data to
Assess Childhood Obesity. PLoS One,
2013; 8(6): e66192.
Last updated: 01/09/2024