This broad category includes non-disease-specific abnormalities or clinical findings, such as fever, fatigue, growth delay, or abnormal lab or imaging results. These findings may represent early indicators of disease or persistent unexplained symptoms. Phenotype logic often incorporates symptom codes, encounter notes, clinical measurements, and temporal patterns. These variables may serve as inclusion/exclusion criteria or outcome measures in phenotyping. Example phenotypes may include “Fever of Unknown Origin,” defined by prolonged elevated temperature with no clear diagnosis, for example.