Glomerular Disease, SNOMED-Only Codes
Abstract
This concept set is inteded to identify patients with a diagnosis of glomerular disease.
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Description
This concept set contains codes pertaining to glomerular disease, glomerulonephritis, nephritic syndrome, and nephrotic syndrome. It is intended to identify a cohort of patients with glomerular disease when incorporated into the computational phenotype originally developed and validated by Denburg et al 2019 (DOI: 10.1681/ASN.2019040365). Validation indicated that this computational phenotype had excellent classification accuracy across PEDSnet: sensitivity, 96% (95% CI, 94% to 97%); specificity, 93% (95% CI, 91% to 94%); positive predictive value (PPV), 89% (95% CI, 86% to 91%); negative predictive value, 97% (95% CI, 96% to 98%).
The computational phenotype identifies patients via two pathways: two or more glomerular inclusion diagnoses on different days of service, OR (one or more glomerular inclusion diagnosis AND one or more kidney biopsy which is not post-transplant). Codes flagged with “other_code_req” alone are not sufficient for a patient to be included in the cohort, i.e., these codes must be accompanied by another code without this flag or a kidney biopsy which is not post-transplant. Codes flagged with “neph_req” must be associated with a nephrology specialty visit.
The concept set was developed by mapping a list of ICD-9-CM codes provided by Michelle Denburg (clinician) to SNOMED. It is limited to SNOMED-CT-only diagnosis codes.
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Related Publications
Denburg, Michelle R.; Razzaghi, Hanieh; Bailey, L. Charles; Soranno, Danielle E.; Pollack, Ari H.; Dharnidharka, Vikas R.; Mitsnefes, Mark M.; Smoyer, William E.; Somers, Michael J. G.; Zaritsky, Joshua J.; Flynn, Joseph T.; Claes, Donna J.; Dixon, Bradley P.; Benton, Maryjane; Mariani, Laura H.; Forrest, Christopher B.2; Furth, Susan L. Using Electronic Health Record Data to Rapidly Identify Children with Glomerular Disease for Clinical Research. JASN 30(12):p 2427-2435, December 2019. | DOI: 10.1681/ASN.2019040365
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