Anti-Asthmatic Agent, Drug Exposure


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dc.contributor.advisorSpergel, Jonathan
dc.contributor.advisorGabryszewski, Stan
dc.contributor.authorHirabayashi, Kathryn
dc.contributor.otherChildren's Hospital of Philadelphia
dc.date.accessioned2026-08-27T12:58:40Z
dc.date.available2024-06-10T19:03:37Z
dc.date.created2024-05-03
dc.date.updated2024-05
dc.descriptionThe new concept set contains asthma medications which include: combination medications (ICS and LABA), zileuton, theophylline, LTRA, LABA, ICS, SABA and Cromolyn, and asthma injections. The new concept set is a more comprehensive list (including descendants) of combination medications (ICS and LABA), zileuton, theophylline, LTRA, LABA, ICS, SABA and Cromolyn, and asthma injections. RxNorm and RxNorm extension codes and descendants were included. This medication list was partially based on an asthma severity computable phenotype published by Peer et al. (2021, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8328264/). The full concept set was not reviewed (descendants caused the list to be very large), but Dr. Jonathan Spergel and Dr. Stan Gabryszewski reviewed the concepts used to generate the list. The concept set was generated to identify patients with an indication of atopic disease, including asthma, and to identify asthma severity based on asthma medications.
dc.description.abstractBroad concept set intended to identify patients with an exposure to an anti-asthmatic agent to identify patient asthma severity.
dc.identifier.urihttps://hdl.handle.net/20.500.14642/642.3
dc.identifier.urihttps://doi.org/10.24373/pdsp-326.3
dc.language.isoen-US
dc.provenanceThis concept set was developed for the "Effect of Dupilumab on Onset of Type 1 Disease" study (Incidence of Autoimmune Diseases in Children with Atopy Treated with Dupilumab) to define a cohort of patients with moderate-to-severe atopic disease, including moderate-to-severe asthma and reused without modification in the Researching COVID to Enhance Recovery (RECOVER) Post-Acute Sequelae of SARS-CoV-2 (PASC) Electronic Health Record (EHR) Cohort Study.
dc.publisherPEDSnet
dc.relation.urihttps://atlassian.chop.edu/bitbucket/projects/PASC/repos/team2_asthma/browse/exploratory.R#202-215
dc.rightsa CC-BY Attribution 4.0 License.
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectIndependent Variable
dc.subjectSensitive
dc.subjectCohort Definition
dc.subject.meshAdrenergic Receptor Agonist
dc.subject.meshSympathomimetic Agent
dc.subject.meshReceptor Agonist
dc.subject.meshNervous System Agent
dc.subject.meshReceptor Interaction
dc.subject.otherRxNorm
dc.subject.otherRxNorm Extension
dc.titleAnti-Asthmatic Agent, Drug Exposure
dspace.entity.typeConceptSet
local.code.githubhttps://github.com/PEDSnet/dupilumab_t1/blob/main/functions/codeset_generation.R#L1179-L1274
local.quality.statusStudy-Specific
local.subject.DataModelPEDSnet Data Model
local.subject.EvalTypeClinician Reviewed
local.subject.MedTermCharBrand Pack Name
local.subject.MedTermCharSemantic Clinical Drug Form
local.subject.MedTermCharSemantic Branded Drug Form
local.subject.MedTermCharIngredient
local.variable.namerx_antiasthmatic
relation.isConceptSetOfConceptSet91fe63bb-b96f-4ab0-a58d-bf7724e04f80
relation.isConceptSetOfConceptSet.latestForDiscovery91fe63bb-b96f-4ab0-a58d-bf7724e04f80
relation.isDocumentationOfConceptSet7156b9cb-99cf-430f-acc6-040fe7398373
relation.isDocumentationOfConceptSet.latestForDiscovery7156b9cb-99cf-430f-acc6-040fe7398373
relation.isStudyOfConceptSet4932bc8c-1f72-44ad-aeeb-b7922e38fad3
relation.isStudyOfConceptSet923eec9d-2cca-497f-9d68-d47643c5654d
relation.isStudyOfConceptSet.latestForDiscovery4932bc8c-1f72-44ad-aeeb-b7922e38fad3

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VersionDateSummary
3*
 2026-08-27 08:55:32
Modified to be more comprehensive list (including descendants) of combination medications (ICS and LABA), zileuton, theophylline, LTRA, LABA, ICS, SABA and Cromolyn, and asthma injections.
2
 2024-09-24 15:19:37
Expanded codeset for Urban Greenspace study.
1
 2024-06-10 15:03:37
Narrow codeset for RECOVER
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