ConceptSet

Anti-coagulant, Drug Exposure


Variable Name

rx_anticoagulant

Refreshed Date

2024-03

Files

1 Download↓
rx_anticoag.csv (1.07 MB)
↓

Tags




Level of Review

Data Model

Vocabularies


Concept set intended to identify patients with an exposure to an anti-coagulant medication.


Variable Status

Funder(s)

Provenance

This concept set was developed for the Computable Phentotypes for Children with Pulmonary Embolism developed as part of the CENTIPEDE pilot study.

Description

Broad concept set intended to assist in defining a cohort of patients with pulmonary embolism; the presence of a prescription or dispensed anti-coagulant acts as inclusion criteria for the cohort.

Medication Term Classes

Clinical Subjects Headings

Development Code

Study Variable Applications

Computable phENotype To Identify Pulmonary Embolism in chilDrEn (CENTIPEDE), Phase II
Study Dates:2025-04 - PresentSponsor Site:Cincinnati Children's Hospital Medical Center
This phase II study is intended to further validate a computable phenotype (CP) developed in phase I which identifies a pediatric pulmonary embolism (PE) cohort from EHR. The accuracy of diagnostic and treatment code combinations using EHR data to diagnose pediatric PE was tested at a single center, the Children"s Hospital of Philadelphia. However, this CP had a high rate of false negatives in children with cardiac disease, likely due to differences in diagnosis and management. This study aims to validate the CP for PE at two additional PEDSnet centers and identify risk categories, develop a CP specific for PE in cardiac patients, and identify PE interventions and outcomes in PEDSnet. This work will allow for comparative effectiveness research and prospective studies using the CP for cohort identification.

Published Research Applications

Data Source

Related Phenotype

Children with Pulmonary Embolism
Refreshed:2024-10-14
Pediatric pulmonary embolism (PE) research has been limited by rarity at individual centers and a lack of multi-center data sources to investigate treatments and outcomes. The goal of this work was to develop a computable phenotype and utilize it in PEDSnet to compare management strategies and outcomes in a validated cohort of children with PE to improve PE care in children.

Related Person

Related Concept Set

Related Code

Creative Commons license

a CC-BY Attribution 4.0 License.
Except where otherwised noted, this item's license is described as a CC-BY Attribution 4.0 License.