Sensitivity to Selection Criteria Study Results: PRESERVE
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Abstract
The results of a Sensitivity to Selection Criteria check using the Multi-Site, Exploratory, Cross-Sectional parameters. This check compares the original PRESERVE attrition cohort to an alternate cohort that requires patients to have >= 5 eGFR measurements >= 180 days apart.
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This data quality check was run on a database extracted from the The Preserving Kidney Function in Children With CKD (PRESERVE) Study. These results were not used for the study, but rather run on the study data after analysis was conducted as part of an SSQDA demonstration project.
Description
- The demographic distribution of both cohorts is generally the same.
- Patients meeting the alternate cohort definition generally enter the cohort at a younger age, have longer follow up, and have a higher median number of facts. This cohort also has a higher proportion of patients with a hypertension diagnosis compared to the base cohort. This indicates the eGFR requirement is likely pulling in sicker kids who require more care, resulting in more frequent and fact-dense encounters with the health system.
Response to Findings
Study team did not conduct further investigation or data intervention in response to these results because this was a demonstration project intended to highlight the functionality of the SQUBA tool.
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Except where otherwised noted, this item's license is described as a CC-BY Attribution 4.0 License.
Cite this Data Quality Result
Wieand, K. (2025, April). Sensitivity to Selection Criteria Study Results: PRESERVE. [D Q Result]. PEDSpace Knowledge Bank. https://doi.org/10.24373/pdsp-649