Malignancy
| dc.contributor.author | Goodwin Davies, Amy |
| dc.contributor.other | Children's Hospital of Philadelphia |
| dc.contributor.other | PEDSnet Data Coordinating Center |
| dc.date.accessioned | 2025-06-03T14:39:21Z |
| dc.date.created | 2025-02 |
| dc.description | The malignancy computable phenotype will identify a cohort of patients meeting criteria for malignancy (cancer) based on diagnoses and drug exposures. ##### Inclusion Criteria This phenotype employs a hierarchical inclusion criteria structure with three tiers. Patients are assessed for Criteria A, assessed for Criteria B if they do not meet Criteria A, and are assessed for Criteria C if they do not meet criteria for A or B. The criteria are: - A: >= 2 cancer diagnoses separated by >= 90 days - B: >= 2 chemotherapy exposures separated by >= 90 days AND >= 1 cancer diagnosis associated with a chemotherapy exposure - C: >= 1 cancer diagnosis and >= 1 chemotherapy exposure separated by >= 90 days AND >= 1 cancer diagnosis associated with a chemotherapy exposure ##### Exclusion Criteria No explicit exclusion criteria are applied to this phenotype. |
| dc.description.abstract | A phenotype for identifying patients with malignancy based on cancer diagnoses and chemotherapy drug exposures. Downloadable content for this Phenotype includes two R files (cohorts.R and driver.R) and a specs folder, which includes the related concept sets linked below. |
| dc.identifier.uri | https://hdl.handle.net/20.500.14642/1053 |
| dc.identifier.uri | https://doi.org/10.24373/pdsp-6 |
| dc.provenance | Developed as part of the Preserving Kidney Function in Children with Chronic Kidney Disease (PRESERVE) study. |
| dc.publisher | PEDSnet |
| dc.relation.uri | https://github.com/PRESERVE-Coordinating-Center/PRESERVE_Variables/blob/main/analytic_code/malignancy_phenotype.R |
| dc.rights | a CC-BY Attribution 4.0 license. |
| dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ |
| dc.subject | Rules-Based (Structured Data-Only) |
| dc.subject.mesh | Neoplasms |
| dc.subject.other | ICD-10 |
| dc.subject.other | ICD-9-CM |
| dc.subject.other | ICD-9-CM |
| dc.subject.other | SNOMED |
| dc.subject.other | RxNorm |
| dc.subject.other | RxNorm Extension |
| dc.title | Malignancy |
| dspace.entity.type | Phenotype |
| local.quality.status | Research-Ready |
| local.subject.DataModel | PCORnet Data Model |
| local.subject.DevPop | Any Age Patient Population |
| local.subject.DevPop | Any Gender Patient Population |
| local.subject.DevPop | Any Race/Ethnicity Patient Population |
| local.subject.validation | No Validation |
| local.variable.name | dx_malignancy |
| relation.isConceptSetOfPhenotype | dfa121f7-b61b-41eb-bcc2-2290009a6e6c |
| relation.isConceptSetOfPhenotype | 9356ae7f-9031-4960-a15b-f2b9e356f24e |
| relation.isConceptSetOfPhenotype.latestForDiscovery | dfa121f7-b61b-41eb-bcc2-2290009a6e6c |
| relation.isDocumentationOfPhenotype | fc7538fd-56d6-44da-96b1-22b9c8fda34e |
| relation.isDocumentationOfPhenotype.latestForDiscovery | fc7538fd-56d6-44da-96b1-22b9c8fda34e |
| relation.isStudyOfPhenotype | 6df51ca1-7a01-4551-b1f1-ca70aaf2c5ae |
| relation.isStudyOfPhenotype.latestForDiscovery | 6df51ca1-7a01-4551-b1f1-ca70aaf2c5ae |
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