Principal Investigators: Michael David Kappelman, MD, MPH

Anti-TNF Monotherapy versus Combination Therapy with Low Dose Methotrexate in Pediatric Crohn’s Disease (The COMBINE Study)

Crohn’s disease causes inflammation in the intestines and stomach, leading to long-term diarrhea and stomach pain. It can also lead to growth problems and lower quality of life. For children, the illness can get worse over time.Doctors treat Crohn’s disease with antibiotics, steroids, or anti-TNF medicines. Anti-TNF medicines help reduce inflammation. Along with anti-TNF medicines, […]

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