Skeletal and Cranial Growth Among Children with Achondroplasia
Achondroplasia, the most common form of disproportionate short stature, is caused by a mutation in the fibroblast growth factor receptor 3 (FGFR3) gene. Affected children may experience severely impaired foramen magnum growth during the first years of life, which may necessitate neurosurgical intervention. The skeletal abnormalities seen in achondroplasia can result in respiratory and neurologic […]