Principal Investigators: Yong Chen

A Distributed Learning Framework for Integrating Evidence in Clinical Research Networks

Rare events such as gastrointestinal bleeding, clinical sites independently often contain insufficient number of cases leading to challenges in characterizing the effect sizes of risk factors for adverse events and conducting accurate risk prediction. Individual patient-level information at each site is often protected by privacy regularities and rules, and direct data integration across multiple clinical […]

A Two-Stage Meta-Regression Framework for Precision Medicine Using Data from Clinical Data Research Networks

Pediatric Chron’s Disease (PCD) is a chronic inflammatory bowel disease (IBD) that has been recognized as one of the most important chronic diseases that affect children and adolescents, with increasing incidence in youth of varying ages. Literature presents gaps in understanding how to synthesize partial or pieces of evidence from multiple sites using distributed analysis […]

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