2026

Year of Publication: 2026

External Validation, Recalibration, and Extension of a Prediction Model of Early Acute Kidney Injury in Critically Ill Children Using Multicenter Data

Title: Helping Doctors Spot Kidney Problems Early in the ICU Key Words: Acute Kidney Injury (AKI), PEDSnet, ICU, prediction model, children Doctors want to find kidney problems early in children who are very sick in the ICU. This study looked at how well a computer model could predict which kids might develop acute kidney injury (AKI) […]

Patient Voices Leading Change: A Call to Action for Careful, Kind, and Connected Patient-Partnered Research in PCORnet®

  Patients Helping Shape Research: How PCORnet and PEDSnet Are Making Studies Better Key Words: patient voices, PEDSnet, PCORnet, research partnership, families, clinical studies This study explains how a national research network called PCORnet is helping patients take part in health research. PCORnet brings together many hospitals and clinics and uses health data from over […]

Beyond Missingness: Systematizing Methods for Comprehensive Data Fitness Assessment in Clinical Research

Razzaghi H, Wieand K, Dickinson K, Kahn M, Roy J, Blacketer C, Christakis D, Forrest C, Greenberg J, Lehmann H, Marsolo K, Sciolla J, Weiner M, Weiskopf N, Bailey L Beyond Missingness: Systematizing Methods for Comprehensive Data Fitness Assessment in Clinical Research J Med Internet Res 2026;28:e76398 URL: https://www.jmir.org/2026/1/e76398 DOI: 10.2196/76398

Growth in Children with a Cleft Lip and/or Palate in 8 US Hospitals: A Retrospective Cohort Study

Title: How Babies With Cleft Conditions Grow in Their First 18 Months Key Words: PEDSnet, cleft lip, cleft palate, infant growth, weight and length This study looked at how babies with cleft lip and/or cleft palate grow during their first year and a half of life. Researchers used medical records from eight children’s hospitals in […]

Incidence of Autoimmune Diseases in Children with Atopy Treated with Dupilumab

Title: Learning About Medicine Safety for Kids Using PEDSnet Data Key Words: PEDSnet, dupilumab, atopic dermatitis, asthma, autoimmune disease Doctors use a medicine called dupilumab to help children with atopic conditions, like eczema and asthma. This study used information from 10 children’s hospitals in the PEDSnet network to learn more about autoimmune diseases in children with atopic […]

Strategies for the development of sodium-glucose cotransporter-2 inhibitors for kidney protection in pediatric chronic kidney disease: proceedings of a workshop meeting in July 2023

Smoyer WE, Gillespie BS, Oni L, Nester C, Nelson RG, Bjornstad P, Heerspink HJL, Denburg M, Gross O, Marquard J, Steubl D, Lim MD, Creighton C, Balogun S, Eva L, Helm K, Tarnoff JM, Tuchman S, Khurana M, Mulugeta L, Yao L, Mistry K, Thompson A, Trachtman H. Strategies for the development of sodium-glucose cotransporter-2 […]

Leveraging the PEDSnet clinical research network and electronic health record data to enhance efficiency of trial enrollment for a rare pediatric rheumatic disease

Title: Finding Kids With Rare Arthritis Using the PEDSnet Network Key Words: PEDSnet, juvenile spondyloarthritis, rheumatology, rare diseases, clinical trials This study looked at how well the PEDSnet network can help doctors find children with juvenile spondyloarthritis, a rare type of arthritis. Researchers used electronic health records from eight children’s hospitals to identify kids with different […]

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