The All of Us Research Program (https://allofus.nih.gov) is a national initiative that is enrolling participants who reflect the diversity of the United States, to build the largest and most diverse biomedical research repository. Recently, the All of Us Research program started a new initiative to enroll at least 150,000 pediatric participants to build a diverse biomedical pediatric dataset that will be available for research. The All of Us research team is collaborating with PEDSnet to estimate representation of health conditions in populations similar to those from whom their participants will be recruited.
All of Us Research Program Pediatric Enrollment: Estimating the phenotypes landscape in Future Pediatric Research Repository
Funding Source:
Participating PEDSnet Sites:
- Children’s Hospital of Philadelphia
- Cincinnati Children’s Hospital Medical Center
- Ann & Robert H. Lurie Children’s Hospital of Chicago
- Children’s National Hospital
- Nationwide Children’s Hospital
- Nemours Children’s Health
- Seattle Children’s Hospital
- Texas Children’s Hospital
Study Investigator:
Vasoactive Selection in Pediatric Septic Shock and the Use of Cardiac Point-of-Care Ultrasound: A Retrospective Registry Analysis Across Multicenter Pediatric Emergency Medicine and Pediatric Critical Care
Pediatric septic shock requires rapid recognition of cardiovascular failure and timely treatment to restore adequate tissue perfusion. Vasoactive medications are central to management, yet considerable uncertainty remains regarding the optimal first‑line agent. Although guidelines recommend tailoring vasoactive choice to a…
Childhood Neighborhood Exposures and Pediatric Multiple Sclerosis
Question 1: How can we identify children with MS using ICD-10 codes in the PEDSnet dataset Question 2: How do neighborhood exposures influence the risk of pediatric MS development Aim 1: Validate a computable phenotype to identify pediatric MS. Aim…
Preventing Suicide among Sexual and Gender Diverse Youth
Suicide is the second leading cause of death among young adults in the United States. Sexual and gender diverse young adults (SGDYA) are at particularly high risk. SGDYA includes individuals who are lesbian, gay, bisexual, transgender, queer, or of another…