Spondyloarthritis is a type of arthritis that affects the spine and joints. It affects one in three youth with arthritis. Spondyloarthritis can cause symptoms like joint pain, back pain, and eye problems.
Doctors often treat this type of arthritis with a type of medicine called a TNFi. A TNFi can help patients become symptom-free. Patients who don’t have symptoms for at least six months have inactive disease. Questions remain about whether patients should continue taking a TNFi once their disease has become inactive.
In this study, the research team is comparing three ways to treat inactive spondyloarthritis:
– Continuing to take a standard TNFi.
– Spacing out the time between TNFi doses.
– Stopping the TNFi.
The research team is looking at the risk of a disease flare with each treatment approach. A disease flare occurs when patients with inactive disease start to have symptoms again.
Biologic Abatement and Capturing Kids’ Outcomes and Flare Frequency in Juvenile Spondyloarthritis (“BACK-OFF JSpA”)
Funding Source:
Participating PEDSnet Sites:
- Cincinnati Children’s Hospital Medical Center
- Children’s Hospital of Philadelphia
- Children’s National Hospital
- Ann & Robert H. Lurie Children’s Hospital of Chicago
- Nationwide Children’s Hospital
- Seattle Children’s Hospital
- Nemours Children’s Health
- Texas Children’s Hospital
Study Investigator:
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