ACE Inhibitor, Drug Exposure


Variable Name

rx_aceinhibitor

Created

2024-05-21

Last Modified

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Files

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rx_ace_inhibitor_no_iv.csv (3.85 MB)
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Data Model


Abstract

Concept set intended to identify patients with an ACE inhibitor medication exposure.

Affiliation(s)

PEDSnet Data Coordinating Center

Funder(s)

Provenance

This concept set was developed for the Preserving Kidney Function in Children with Chronic Kidney Disease (PRESERVE) study. It has been reused in the following PEDSnet Projects: - PKDnet: ARPKD Learning Network

Description

This medication concept set includes the following ingredients: Benazepril, Captopril, Enalapril, Fosinopril, Lisinopril, Moexipril, Periondopril, Quinapril,Ramipril, Trandolapril. It also includes combinations of these ingredients with other antihypertensive medications. This concept set, in contrast to its previous version, does NOT contain IV formulations.

This code list was generated by taking the descendants of all the ACE inhibitor ingredients of interest and string matching with the concept_name of the ingredient. The broad concept set was intended to identify patients who received ACE inhibitors. It is limited to NDC, RxNorm, and RxNorm Extension codes. Meds were expected to be only oral/enteral/IV, not topical, ophthalmic/ocular, or buccal.

Development Code

https://github.com/PRESERVE-Coordinating-Center/PRESERVE_Variables/blob/dfe52bdc48cfcfd6b358d4a424b5d39749554025/codesets/drug/rx_ace_inhibitor.csv

Vocabulary

Medication Classification Level










Clinical Subjects Headings

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Data Source

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PEDSnet Nephrology Data Insights
Created:2025-03Affiliation:PEDSnet Data Coordinating Center
This dashboard provides clinical insights into cohorts identified from computable phenotypes for several populations of patients with childhood kidney disease.

#### **Access the PEDSnet Nephrology Data Insights application [here](https://pedsnet.org/ndi/).**

Related Phenotype

Related Person

Related Study

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Preserving Kidney Function in Children with Chronic Kidney Disease (PRESERVE)
Affiliation:Children's Hospital of Philadelphia
Study intended to inform shared decision-making regarding blood pressure management for pediatric chronic kidney disease (CKD).
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PKDnet: ARPKD Learning Network
Affiliation:Children's Hospital of Philadelphia
Study to accelerate clinical trials for autosomal recessive polycystic kidney disease (ARPKD) by creating PKDnet, a robust data resource to identify a research-ready cohort of children with ARPKD and efficiently collect high quality, large-scale natural history data and identify suitable endpoints and prognostic biomarkers to inform clinical trial design.

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Creative Commons license

a CC-BY Attribution 4.0 License.
Except where otherwised noted, this item's license is described as a CC-BY Attribution 4.0 License.

Cite this Concept Set

Utidjian, L. (2024, May). ACE Inhibitor, Drug Exposure. [Concept Set]. PEDSpace Knowledge Bank. https://doi.org/10.24373/pdsp-285.2

Version History

Now showing 1 - 2 of 2
VersionDateSummary
2*
 2024-09-24 13:30:28
This version does NOT contain IV formulations.
1
 2024-06-10 15:03:21
This version DOES contain IV formulations.
* Selected version