ConceptSet

Glomerular Disease, Diagnosed


Variable Name

dx_glomerularDisease

Refreshed Date

2021-03

Tags

Level of Review

Data Model

Vocabularies

This concept set is inteded to identify patients with a diagnosis of glomerular disease.


Variable Status

Funder(s)

Provenance

This glomerular disease concept set was updated for the Comparative Effectiveness of Treatments for Recurrent Focal Segmental Glomerulosclerosis (FSGS) in Pediatric Kidney Transplantation study. The original concept set was developed and used for the Membranoproliferative Glomerulonephritis (MPGN) in PEDSnet study.

Description

This concept set contains codes pertaining to glomerular disease, glomerulonephritis, nephritic syndrome, and nephrotic syndrome. The original concept set was intended to identify a cohort of patients with glomerular disease when incorporated into the computational phenotype originally developed and validated by Denburg et al 2019 (DOI: 10.1681/ASN.2019040365).

The original concept set was developed by mapping a list of ICD-9-CM codes provided by Michelle Denburg (clinician) to SNOMED. This concept set was updated from the original by taking the descendants for and string-matching for the following SNOMED-CT concepts: glomerular disease, glomerulonephritis, nephritic syndrome, nephrotic syndrome. The resulting concept set was combined with the original concept set and further refined via review with Michelle Denburg (clinician).

Medication Term Classes

Clinical Subjects Headings

Development Code

Study Variable Applications

Comparative Effectiveness of Treatments for Recurrent Focal Segmental Glomerulosclerosis in Pediatric Kidney Transplantation
Study Dates:2020 - 2023Sponsor Site:St. Louis Children's Hospital
Study to compare efficacy and outcomes of various therapies used for recurrent focal segmental glomerulosclerosis (FSGS).
Membranoproliferative Glomerulonephritis (MPGN) in PEDSnet
Study Dates:2019-06 - 2026-07Sponsor Site:Children's Hospital of Philadelphia
Project to identify and conduct phenotypic characterization of children with C3G and IC-MPGN in PEDSnet using data science and chart review methods. The long-term goal of this work is to perform a large multi-institutional natural history study, compare clinical outcomes in C3G and IC-MPGN, and identify predictors of disease response or progression.

Published Research Applications

Data Source

Related Phenotype

Related Person

Related Concept Set

Related Code

Creative Commons license

Except where otherwised noted, this item's license is described as a CC-BY Attribution 4.0 License.


Version History

Now showing 1 - 4 of 4
VersionDateSummary
2026-08-25 16:14:26
Removed SNOMED codes for PRESERVE Glomerular Disease Phenotype.
2026-08-25 16:04:45
Much larger set developed for PRESERVE.
2*
2024-10-07 16:13:28
Updated to be more comprehensive and suitable for reuse.
2024-06-10 15:03:24
Restricted to diagnoses that occurred in the PEDSnet database at the time of creation.
* Selected version