Quantitative Variable Distribution Study Results Part IV: SSDQA Comparison


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2026-02-05
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Findings


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PEDSnet

Abstract

The results of a Quantitative Variable Distribution check using the Multi-Site, Exploratory, Cross-Sectional parameters. This check investigates the value distributions of drug metadata fields (days_supply, refills, quantity) relating to hydroxyurea drug exposures.

Affiliation(s)

PEDSnet Data Coordinating Center

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Provenance

Description

  • The distributions here are impacted by low population as evidenced in the Expected Variables Present results, with some sites having limited distributions due to limited population.
  • Stanford has an unusually broad range of quantity values when compared to the rest of the network. These values are likely implausible and will require further investigation.
  • Days supply & refills both have high variability amongst sites, but the ranges for sites where those fields are well populated are generally within the expected range.

Response to Findings


Given the variability and implausibility of values in these distributions, we will instead opt to rely on drug exposure start & end dates to establish drug exposure windows for the analysis. More DQ investigation will be done to investigate Stanford's quantity values.

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Data Source

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Institutions

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Children's National Hospital
Serving the nation’s children for more than 150 years, Children’s National Hospital has been an innovator in pediatric health care around the nation and around the world. Children’s National was one of the nation’s first children’s hospitals, opening in 1870 and growing from a modest 12-bed facility to a 323-bed facility that performs more than 17,000 surgeries and conducts more than 669,000 outpatient visits in more than 60 specialties each year. Formerly referred to as D.C. Children’s Hospital, Children’s National is the only exclusive provider of pediatric care in the Washington, D.C., metropolitan area. Today, the health system includes primary care health centers, regional outpatient centers, and affiliated pediatric primary and specialty care practices throughout the metropolitan area, in addition to providing tertiary care in our main hospital.
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Ann & Robert H. Lurie Children's Hospital of Chicago
Lurie Children's works to provide the best possible care for patients and their families. More than 239,000 children receive the highest-quality medical care at Lurie Children’s each year. Lurie Children’s treats more children insured by Medicaid than any other hospital in Illinois.
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Cincinnati Children's Hospital Medical Center
Founded in 1883, CCHMC is a 628-bed children’s hospital, and is the only specialized pediatric provider in the Cincinnati metropolitan area (population 2.3 million). CCHMC provides primary care through 4 primary care centers (called Pediatric Primary Centers or PPCs) located in Cincinnati and Eastern Indiana. Pediatric primary care is also provided by 303 affiliated primary care practices within CCHMC’s 8 county primary market and an additional 143 affiliated primary care practices in CCHMC’s 17 county secondary market. Primary care clinical research is conducted both at the PPCs and by the Cincinnati Pediatric Research Group (CPRG). Founded in 1996, the CPRG is a Midwest regional practice-based research network that provides an infrastructure to catalyze community-academic research partnerships. Half of the pediatric practices in the Greater Cincinnati Region have participated in a research or a quality improvement project in the past 6 years. CCHMC also has 11 Specialty Care Centers that provide the spectrum of outpatient subspecialty services in locations throughout the Greater Cincinnati region. Over the past 12 months, the CCHMC system managed 33,692 admissions, 102,557 ED visits, 84,711 primary care patients, 852,899 specialty visits, and 32,300 surgeries for a total of 1.2M visits.
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Children's Hospital Colorado
Children’s Hospital Colorado (Children’s Colorado) has defined and delivered pediatric health care excellence for more than 100 years. Founded in 1908, Children’s Colorado is a leading pediatric network entirely devoted to the health and well-being of children. Continually acknowledged as one of the nation’s outstanding pediatric hospitals by U.S. News & World Report and ranked 5th on its Best Children’s Hospitals 2015-16 Honor Roll, Children’s Colorado is known for both its nationally and internationally recognized medical, research, education and advocacy programs, as well as comprehensive everyday care for kids throughout Colorado and surrounding states. Children’s Colorado is the winner of the 2015 American Hospital Association-McKesson Quest for Quality Prize, and is a 2015 Most Wired hospital according to Hospitals & Health Networks magazine. Children’s Colorado also is recognized for excellence in nursing from the American Nurses Credentialing Centers and has been designated a Magnet® hospital since 2005. The hospital’s family-centered, collaborative approach combines the nation’s top pediatric doctors, nurses and researchers to pioneer new approaches to pediatric medicine. With urgent, emergency and specialty care locations throughout Metro Denver and Southern Colorado, including its campus on the Anschutz Medical Campus, Children’s Colorado provides a full spectrum of pediatric specialties.
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Children's Hospital of Philadelphia
Founded in 1855, CHOP is the nation’s oldest hospital dedicated solely to the care of children. The Main Hospital has 500 beds, 40 percent of which are allocated to intensive care with over 24,000 inpatient admissions per year. CHOP is the community hospital and primary care center for children in West and South Philadelphia, and a major tertiary referral center for the greater Delaware Valley area with an estimated population of 10 million. CHOP serves a diverse population of children that includes large numbers of racial and ethnic minorities, healthy newborns, infants, children and adolescents. CHOP provides primary care through its extensive network of 31 Primary Care Centers, which care for ~250,000 patients per year, located in Philadelphia, southern New Jersey, and northern Delaware. The CHOP primary care network is organized as a practice-based research network called PeRC, which receives institutional infrastructure support for recruitment into projects. Ten large Specialty Care Centers provide a comprehensive range of outpatient subspecialty services in locations throughout the metropolitan area. Overall, there are nearly 2 million patient visits made to CHOP by 400,000 unique patients. The CHOP Emergency Room manages >90,000 patient visits per year.

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Cite this Data Quality Result

Wieand, K. (2026, February). Quantitative Variable Distribution Study Results Part IV: SSDQA Comparison. [D Q Result]. PEDSpace Knowledge Bank. https://doi.org/10.24373/pdsp-500