Children with Pulmonary Embolism

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dc.contributor.authorZelinski, Ally
dc.contributor.otherPEDSnet Data Coordinating Center
dc.date.accessioned2025-03-25T18:24:48Z
dc.date.created10/14/24
dc.descriptionThis computable phenotype is based on the ASPECT algorithm developed for adult PE with removed exclusion criteria from Version 1. The algorithm was used to identify a pediatric pulmonary embolism (PE) cohort from electronic health records (EHR) and evaluate the accuracy of diagnostic and treatment code combinations using EHR data to diagnose pediatric PE at a single center, the Children’s Hospital of Philadelphia. Performance based on chart review: <br> >> sensitivity = 96% <br> >> specificity = 88% <br> >> PPV = 90% <br> >> NPV = 95% ##### Inclusion Criteria: - PE diagnosis code associated with an inpatient or emergency department visit; - CT or perfusion scans performed during or <= 2 days prior to the visit; - Anticoagulant dispensed or prescribed during the visit. ##### Exclusion Criteria: None
dc.description.abstractPediatric pulmonary embolism (PE) research has been limited by rarity at individual centers and a lack of multi-center data sources to investigate treatments and outcomes. The goal of this work was to develop a computable phenotype and utilize it in PEDSnet to compare management strategies and outcomes in a validated cohort of children with PE to improve PE care in children.
dc.identifier.urihttps://pedsnet.org/metadata/handle/20.500.14642/922.2
dc.provenanceThis computable phenotype was created for the pilot study, Computable phENotype To Identify Pulmonary Embolism in chilDrEn (CENTIPEDE).
dc.publisherPEDSnet
dc.relationPediatric Pulmonary Embolism
dc.relationComputed Tomography (CT Scan)
dc.relationAnti-coagulants
dc.relation.urihttps://atlassian.chop.edu/bitbucket/projects/PRP/repos/centipede/browse/computational_phenotypes/code
dc.rightsa CC-BY Attribution 4.0 license.
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectComputable Phenotyping::Content Data Model::PEDSnet Data Model
dc.subjectComputable Phenotyping::Phenotype Development Strategy::Rules-Based (Structured Data-Only)
dc.subjectComputable Phenotyping::Variable Characterization::Cohort Definition (Inclusion or Exclusion Criteria)
dc.subjectComputable Phenotyping::Development Population::Age Groups::Child Patient Population
dc.subjectConcept Set Development::Concept Set Evaluation::Chart Reviewed
dc.subject.meshPulmonary Embolism
dc.subject.meshLung Diseases
dc.subject.meshRespiratory Tract Diseases
dc.subject.meshEmbolism and Thrombosis
dc.subject.meshVascular Diseases
dc.subject.otherSNOMED
dc.subject.otherCPT
dc.subject.otherICD-10-PCS
dc.subject.otherOPCS4
dc.subject.otherRxNorm
dc.subject.otherRxNorm Extension
dc.titleChildren with Pulmonary Embolism
dspace.entity.typePhenotype
local.quality.statusResearch-Ready
local.subject.flatPEDSnet Data Model
local.subject.flatRules-Based (Structured Data-Only)
local.subject.flatCohort Definition (Inclusion or Exclusion Criteria)
local.subject.flatChild Patient Population
local.subject.flatChart Reviewed
local.subject.flatAny Gender Identity Patient Population
relation.isConceptSetOfPhenotype3f6753bf-0bfe-465c-a270-e04d4b49b39d
relation.isConceptSetOfPhenotype2a77461f-47d2-4094-8a11-7f72a036d25c
relation.isConceptSetOfPhenotyped2d0e52c-dd2e-4f96-a1a6-d204dea95e3c
relation.isConceptSetOfPhenotype.latestForDiscovery3f6753bf-0bfe-465c-a270-e04d4b49b39d
relation.isStudyOfPhenotypede3901f5-39a7-4ab0-9666-d43f9c209e4d
relation.isStudyOfPhenotype.latestForDiscoveryde3901f5-39a7-4ab0-9666-d43f9c209e4d

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Diagnosis Phenotypes

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VersionDateSummary
2*
 2025-03-25 14:20:18
Removed an exclusion criteria from original resulting in better performance.
1
 2024-12-20 11:17:26
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