Kidney Transplant

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dc.contributor.authorNguyen, Nhat
dc.contributor.authorHirabayashi, Katie
dc.contributor.otherChildren's Hospital of Philadelphia
dc.contributor.otherPEDSnet Data Coordinating Center
dc.date.accessioned2025-03-12T15:48:51Z
dc.date.created2025-03
dc.descriptionThe computable phenotype was developed to query patients who had undergone kidney transplant and was validated against USRDS dataset and a subset of chart review patients. The most optimal algorithm for identifying children with kidney transplant used one code from Group A (more specific) and two distinct codes from Group B (more sensitive), achieving the following performance metrics: <br> <br> - **F1 Score:** 0.93 (95% CI 0.89-0.97)<br> - **PPV:** 90.7% (95% CI 84.2%-95.8%)<br> - **Sensitivity:** 96.0% (95% CI 91.8%-100.0%)
dc.description.abstractA phenotype to identify patients with chronic kidney dialysis based on a combination of broad and chronic dialysis procedure and condition codes, and eGFR values. Downloadable content for this Phenotype includes two R files (cohorts.R and driver.R) and a specs folder, which includes the required concept sets.
dc.identifier.urihttps://hdl.handle.net/20.500.14642/980
dc.provenanceThis phenotype was developed for the Preserving Kidney Function in Children with Chronic Kidney Disease (PRESERVE) study.
dc.publisherPEDSnet
dc.relationKidney Transplant
dc.relation.urihttps://github.com/PRESERVE-Coordinating-Center/PRESERVE_Variables/blob/main/analytic_code/kidney_transplant_cp_USRDS.R
dc.rightsa CC-BY Attribution 4.0 license.
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectComputable Phenotyping::Content Data Model::PCORnet Data Model
dc.subjectComputable Phenotyping::Phenotype Evaluation::Validated
dc.subjectComputable Phenotyping::Phenotype Development Strategy::Rules-Based (Structured Data-Only)
dc.subject.meshKidney Transplantation
dc.subject.meshRenal Replacement Therapy
dc.subject.meshOrgan Transplantation
dc.subject.meshUrologic Surgical Procedures
dc.subject.otherICD-10-PCS
dc.subject.otherSNOMED
dc.subject.otherICD-10-GM
dc.subject.otherCPT
dc.subject.otherICD-10-CM
dc.subject.otherICD-9-CM
dc.titleKidney Transplant
dspace.entity.typePhenotype
local.quality.statusResearch-Ready
local.subject.DataModelPCORnet Data Model
local.subject.DevPopAny Age Patient Population
local.subject.DevPopAny Gender Identity Patient Population
local.subject.DevPopAny Race/Ethnicity Patient Population
local.subject.flatRules-Based (Structured Data-Only)
local.subject.validationExternal Standard
local.subject.validationClinical Chart Review
relation.isConceptSetOfPhenotype09c2d231-d02b-4c7f-a68f-c8edf2bae282
relation.isConceptSetOfPhenotype.latestForDiscovery09c2d231-d02b-4c7f-a68f-c8edf2bae282
relation.isStudyOfPhenotype6df51ca1-7a01-4551-b1f1-ca70aaf2c5ae
relation.isStudyOfPhenotype.latestForDiscovery6df51ca1-7a01-4551-b1f1-ca70aaf2c5ae

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Urogenital Phenotypes