Kidney Transplant

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Phenotype Description

A phenotype to identify patients with chronic kidney dialysis based on a combination of broad and chronic dialysis procedure and condition codes, and eGFR values.

Downloadable content for this Phenotype includes two R files (cohorts.R and driver.R) and a specs folder, which includes the required concept sets.

Funder(s)

Provenance

This phenotype was developed for the Preserving Kidney Function in Children with Chronic Kidney Disease (PRESERVE) study.

Algothrithm Description

The computable phenotype was developed to query patients who had undergone kidney transplant and was validated against USRDS dataset and a subset of chart review patients.

The most optimal algorithm for identifying children with kidney transplant used one code from Group A (more specific) and two distinct codes from Group B (more sensitive), achieving the following performance metrics:

  • F1 Score: 0.93 (95% CI 0.89-0.97)
  • PPV: 90.7% (95% CI 84.2%-95.8%)
  • Sensitivity: 96.0% (95% CI 91.8%-100.0%)

Data Source

Related Concept Set

Kidney Transplant
(2024-01) Children's Hospital of Philadelphia; University of Michigan
Concept set intended to identify patients having undergone a kidney transplant procedure. This concept set was validated against United States Renal Data System (USRDS) data.

Related Person

Related Phenotype

Related Study

Preserving Kidney Function in Children with Chronic Kidney Disease (PRESERVE)
Children's Hospital of Philadelphia
Study intended to inform shared decision-making regarding blood pressure management for pediatric chronic kidney disease (CKD).

Related Publications

Creative Commons license

Except where otherwised noted, this item's license is described as a CC-BY Attribution 4.0 license.