Founded in 1883, CCHMC is a 628-bed children’s hospital, and is the only specialized pediatric provider in the Cincinnati metropolitan area (population 2.3 million). CCHMC provides primary care through 4 primary care centers (called Pediatric Primary Centers or PPCs) located in Cincinnati and Eastern Indiana. Pediatric primary care is also provided by 303 affiliated primary care practices within CCHMC’s 8 county primary market and an additional 143 affiliated primary care practices in CCHMC’s 17 county secondary market. Primary care clinical research is conducted both at the PPCs and by the Cincinnati Pediatric Research Group (CPRG). Founded in 1996, the CPRG is a Midwest regional practice-based research network that provides an infrastructure to catalyze community-academic research partnerships. Half of the pediatric practices in the Greater Cincinnati Region have participated in a research or a quality improvement project in the past 6 years. CCHMC also has 11 Specialty Care Centers that provide the spectrum of outpatient subspecialty services in locations throughout the Greater Cincinnati region. Over the past 12 months, the CCHMC system managed 33,692 admissions, 102,557 ED visits, 84,711 primary care patients, 852,899 specialty visits, and 32,300 surgeries for a total of 1.2M visits.