PEDSnet Studies

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Vasoactive Selection in Pediatric Septic Shock and the Use of Cardiac Point-of-Care Ultrasound: A Retrospective Registry Analysis Across Multicenter Pediatric Emergency Medicine and Pediatric Critical Care

Pediatric septic shock requires rapid recognition of cardiovascular failure and timely treatment to restore adequate tissue perfusion. Vasoactive medications are central to management, yet considerable uncertainty remains regarding the optimal first‑line agent. Although guidelines recommend tailoring vasoactive choice to a…

Ischemic Stroke Incidence and Risk Factors in Adults with Congenital Heart Disease

It is well known that adults with CHD have higher rates of stroke and stroke at younger ages, compared to the general population. We aim to better characterize this risk in a large US patient population, and to better understand…

Cardiometabolic Risk Factors in Children with Congenital Heart Disease

Rationale – Children with congenital heart disease (CHD) have increased cardiovascular risk (CV)​ – Cardiometabolic risk factors are infrequently evaluated in children with CHD​ – Implementation gap between guidelines and actual practice​ Aims – Define prevalence of cardiometabolic risk factors…

Achieving Equity: Inclusion of Adults with Congenital Heart Disease (CHD) Living with Neurodevelopmental Disorders (NDDs) in Patient-Centered Outcomes Research

Congenital heart disease (CHD) is an abnormality of the heart that patients are born with, and it is the most common birth defect, occurring in about one in 100 births. Because of better medical and surgical care, adults with CHD…

NEST R2: Characterization and Utilization of Therapeutic Cardiac Devices in Children with Congenital Heart Disease

Utilizing the Electronic Health Record (EHR) to capture the use of implantable devices during congenital cardiac catheterization procedures across multiple institutions has not been previously possible. In this Test Case sponsored by the National Evaluation System for Health Technology Coordinating…

Does Receiving Guidelines-Based Care Improve Health Outcomes for Adults with Congenital Heart Defects? — The CHI-RON Study

Congenital heart defects, or CHDs, are the most common type of birth defect. CHDs can be noncomplex or complex. Examples of noncomplex CHDs include an issue with one heart valve or a hole in the heart. Complex CHDs may affect…

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