Long-term Neurodevelopmental Effects in Neonates Following Treatment with Lacosamide
The Neurodevelopmental Outcomes Study is a retrospective, observational cohort study designed to compare the long-term neurocognitive outcomes of neonates treated with lacosamide versus other antiseizure medications (ASMs) for neonatal seizures. Neonatal seizures, which occur in 1.4 to 3.6 per 1,000…
Long-term Neurocognitive Effects in Neonates Following Treatment with Lacosamide
The Neurocognitive Developmental Outcomes Study is a retrospective, observational cohort study designed to compare the long-term neurocognitive outcomes of neonates treated with lacosamide versus other antiseizure medications (ASMs) for neonatal seizures. Neonatal seizures, which occur in 1.4 to 3.6 per…
Characterization of Babies Born with Hemolytic Disease of the Fetus/Newborn (HDFN)
Hemolytic disease of the fetus and newborn (HDFN) otherwise known as erythroblastosis fetalis, is a disease in which fetal and neonatal erythrocytes are destroyed by maternal IgG alloantibodies. Before the first RhD immunoprophylaxis was introduced as a treatment in 1968,…
Hemolytic Disease of the Fetus and Newborn (HDFN) Epidemiology Study
The Hemolytic Disease of the Fetus and Newborn (HDFN) Epidemiology Study aims to analyze the epidemiology and clinical outcomes of HDFN using data from the PEDSnet database. HDFN, caused by maternal IgG alloantibodies that destroy fetal and neonatal erythrocytes, remains…
Pharmacokinetics in Neonates Exposed to Lacosamide
Seizures are one of the most common neurologic emergencies in neonates, arising in ~3/1000term live births and are associated with significant mortality and neuro-developmental disability (Soul et al, 2018). In contrast to seizures in older children, most neonatal seizures result…
Retrospective cohort study evaluating treatment pathways through care and potential adverse events in neonatal seizures
Seizures are one of the most common neurologic emergencies in neonates, arising in ~3/1000 term live births and are associated with significant mortality and neuro-developmental disability (Soul et al, 2018). In contrast to seizures in older children, most neonatal seizures…
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