Health systems use quality measures to assess how well they deliver care to patients. These measures require accurate data. Health systems often do a manual medical chart review to get accurate data. To do a manual review, staff combine data from a number of patient health records. This process is expensive and takes time. PCORI […]
Crohn’s disease causes inflammation in the intestines and stomach, leading to long-term diarrhea and stomach pain. It can also lead to growth problems and lower quality of life. For children, the illness can get worse over time.Doctors treat Crohn’s disease with antibiotics, steroids, or anti-TNF medicines. Anti-TNF medicines help reduce inflammation. Along with anti-TNF medicines, […]
Given the increasing prevalence and significant morbidity of pediatric ulcerative colitis (UC), it is imperative that we understand and define all knowledge gaps related to this disease. Adult data suggest that despite improved outcomes with newer medications, surgical outcomes have deteriorated. In children and adolescents with UC, surgical indications and outcomes are not well defined, […]
RebeElectronic health records (EHR) provide extensive information on disease risk factors that can be studied to improve our understanding of health outcomes. However, medical assessments are performed at irregular intervals in response to patients’ medical needs, which makes these data difficult to use for research. This project will develop new statistical methods that combine the […]
Bariatric surgery has been used for treatment of severe obesity in adolescents but most studies have been small and limited in follow-up. We hypothesized that electronic health record data could be used to compare effectiveness of bariatric procedures in adolescents. Data were obtained from clinical research networks using a common data model to extract data […]
Our aim is to implement and test electronic measures of outpatient pediatric healthcare quality and safety using the PCORI Common Data Model.The PCORnet Common Data Model is a way of organizing data, including data mined directly from the electronic health record, into a standard structure. This research will take place in two PCORI funded networks […]
The objectives of the proposed study are to assess the effects of different types, timing, and amount of antibiotic use in the first two years of life with (Specific Aim 1) body mass index (BMI) and obesity at ages 5 and 10 years and (Specific Aim 2) growth trajectories to age 5 years. In Specific […]
The goal of this project was to investigate potential associations between weight status and clinical outcomes of children treated for viral or bacterial lower respiratory tract infections or asthma. Our hypothesis was that children with overweight and obesity will have more hospitalizations and will require increased resource utilization compared to children with weight in the […]
This is a retrospective observational study using a national sample with a pairwise treatment comparison in a so‐called ‘matrix model’ design. The aim of this study is to evaluate the comparative risks for serious infections, cardiovascular events, and incident cancer associated with biologics and non‐biologic therapies used for the treatment of adult and pediatric Autoimmune […]
Healthy Weight Network is a group of pediatric weight management cinches at the eight children’s hospitals that comprise A National Pediatric Learning Health (PEDSnet) and 3 sites within Scalable Collaborative Infrastructure for a Learning Health. The purpose of this study is to: 1. Demonstrate the viability of the clinic consortium to feasibly 2. Survey a […]