Assessment of Pediatric Radiation Exposure from Computed Tomography

The objective of this study is to identify pediatric cohorts with the highest levels of radiation exposure from CT scanning by merging EMR data elements with an automated method for calculating cumulative, patient level radiation exposure. The results of this study will serve as preliminary data for a PEDSnet application to PCORI. The goal of which would be to (1) study this process prospectively in additional PCORnet networks that treat both children and adults and; (2) develop and implement multi-institutional efforts to reduce CT scanning in high risk cohorts through partnership with networks such as Image Gently or Solutions for Patient Safety.
This is an observational study. It will include all pediatric patients aged 0 to 15 years who receive CT scans of the head, chest, abdomen, and pelvis.
The retrospective data will be pulled from both Digital Imaging and Communications in Medicine (DICOM) files or similar types of files via PACS, and EMR data from January 1, 2012 – December 31, 2014 at all participating PEDSnet institutions.
Information will be automatically abstracted from the imaging file as well as their electronic medical record (EMR) and sent to a secure research workstation.

Clinical Outcomes by Language of Care in Pediatric Oncology

Although language disparities in outcomes are well documented in general pediatrics and adult oncology, little is known in pediatric oncology. Patient or family language is not included in many multi- institutional databases and patient registries, limiting studies of language-based inequities…

Extreme weather impacts on children’s acute and chronic health outcomes; a multisite study with evaluation of vulnerabilities

The “Extreme Weather and Pediatric Health Outcomes” study investigates the impact of climate change-related extreme weather events, such as extreme heat and heavy rainfall, on children’s health across the United States. This innovative research aims to address critical knowledge gaps…

Characterization of Babies Born with Hemolytic Disease of the Fetus/Newborn (HDFN)

Hemolytic disease of the fetus and newborn (HDFN) otherwise known as erythroblastosis fetalis, is a disease in which fetal and neonatal erythrocytes are destroyed by maternal IgG alloantibodies. Before the first RhD immunoprophylaxis was introduced as a treatment in 1968,…

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