Glomerular Disease

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Abstract

A phenotype for identifying patients with glomerular disease based on diagnoses and kidney biopsy procedures.

Downloadable content for this Phenotype includes two R files (cohorts.R and driver.R) and a specs folder, which includes the required concept sets.

Funder(s)

Provenance

Developed as part of the Preserving Kidney Function in Children with Chronic Kidney Disease (PRESERVE) study.

Description

The glomerular disease computable phenotype will identify a cohort of patients meeting criteria for glomerular disease based on criteria developed as part of the GLEAN study.

Inclusion Criteria

Broad pathways into the cohort:

  • 2 or more glomerular inclusion diagnoses on different dates OR
  • 1 or more glomerular inclusion diagnoses AND 1 or more kidney biopsy which is not post-transplant Inclusion diagnoses with special requirements:
  • 1 or more “other_code_req” diagnosis AND 1 or more additional glomerular inclusion diagnosis on a different date OR 1 or more kidney biopsy that is not post-transplant
  • 1 or more neph_req diagnosis that is associated with a nephrology visit
Exclusion Criteria
  • Inclusion events occur after age_ub_years (defaults to 30), before the minimum date cutoff or after the maximum date cutoff, or after the patient’s endpoint date
  • Kidney biopsy occurs after a kidney transplant.

Related Concept Set

Kidney Transplant
(2021-11-01) Children's Hospital of Philadelphia
Concept set intended to identify patients having undergone a kidney transplant procedure.
Kidney Biopsy
(2023-04-07) Children's Hospital of Philadelphia
Concept set intended to identify patients having undergone a kidney biopsy procedure.
Glomerular Disease
(2024-01-01) Children's Hospital of Philadelphia
This concept set was created to identify patients with a diagnosis of glomerular disease for implementation of a computational phenotype which was validated using the OMOP data model. The purpose was to identify glomerular disease etiologies of chronic kidney disease.

Related Person

Related Study

Preserving Kidney Function in Children with Chronic Kidney Disease (PRESERVE)
Children's Hospital of Philadelphia
Study intended to inform shared decision-making regarding blood pressure management for pediatric chronic kidney disease (CKD).

Related Phenotype

Related Publications

Creative Commons license

Except where otherwised noted, this item's license is described as a CC-BY Attribution 4.0 license.