PEDSnet Studies

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Comparative Effectiveness Bariatric Surgery

Bariatric surgery has been used for treatment of severe obesity in adolescents but most studies have been small and limited in follow-up. We hypothesized that electronic health record data could be used to compare effectiveness of bariatric procedures in adolescents….

SPARK Registry- PEDSnet Linkage Pilot

The Simons Foundation Powering Autism Research for Knowledge (hereinafter referred to as SPARK)Registry was established to recruit, engage, and retain a community of 50,000 individuals with ASD along with their family members in the United States to identify the causes…

Pediatric Glomerular Disease Learning Network

The goal of this study is to create a sustainable and expandable Pediatric Glomerular Disease Learning Network to address fundamental limitations of current observational cohorts and registries and focus on practice pattern variation, observational outcomes and comparative effectiveness research, and…

Unanticipated Consequences of Proton Pump Inhibitor Use

This study investigates whether genetic variation in CYP2C19 contributes to proton pump inhibitor-associated infections and chronic illness exacerbations in children. Study aims include: 1) To compare rates of infection in healthy and obese children, and children with chronic illnesses of…

Atkinson Systemic Lupus Erythematosis

Aim 1: It is difficult to perform adequate clinical trials in pediatric diseases such as systemic lupus erythematosus (SLE) is a major challenge. To improve strategies necessary for identifying patients for trial recruitment electronic health record (EHR) algorithms were developed and tested…

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