Comparative Effectiveness of Narrow Versus Broad-Spectrum Antibiotic Use On ED Revisit Rates In Pediatric Pneumonia

We propose to evaluate the impact of antibiotic prescribing patterns on hospital revisit rates among children with community acquired pneumonia. 1) Among children discharged from emergency department (ED) with Community-Acquired Pneumonia (CAP), does antibiotic prescribing patterns impact 3-day and 7-day revisit rates? Hypothesis 1: Children receiving amoxicillin do not have higher ED revisit rates compared to children receiving a cephalosporin antibiotic. Hypothesis 2: School age children who receive a macrolide antibiotic (e.g. azithromycin) in combination with amoxicillin are less likely to have an ED revisit compared with children receiving amoxicillin alone. 2) Among children hospitalized with CAP, does antibiotic prescribing patterns impact 30-day readmission rates? Hypothesis 3: Hospitalized children who receive amoxicillin after discharge are less likely to be readmitted within 30-days following discharge compared to children receiving a cephalosporin antibiotic. This will be a retrospective cohort study of children cared for at 8 children’s hospitals included in the PEDSnet database with CAP.

Clinical Outcomes by Language of Care in Pediatric Oncology

Although language disparities in outcomes are well documented in general pediatrics and adult oncology, little is known in pediatric oncology. Patient or family language is not included in many multi- institutional databases and patient registries, limiting studies of language-based inequities…

Extreme weather impacts on children’s acute and chronic health outcomes; a multisite study with evaluation of vulnerabilities

The “Extreme Weather and Pediatric Health Outcomes” study investigates the impact of climate change-related extreme weather events, such as extreme heat and heavy rainfall, on children’s health across the United States. This innovative research aims to address critical knowledge gaps…

Characterization of Babies Born with Hemolytic Disease of the Fetus/Newborn (HDFN)

Hemolytic disease of the fetus and newborn (HDFN) otherwise known as erythroblastosis fetalis, is a disease in which fetal and neonatal erythrocytes are destroyed by maternal IgG alloantibodies. Before the first RhD immunoprophylaxis was introduced as a treatment in 1968,…

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