Ischemic Stroke Incidence and Risk Factors in Adults with Congenital Heart Disease

It is well known that adults with CHD have higher rates of stroke and stroke at younger ages, compared to the general population. We aim to better characterize this risk in a large US patient population, and to better understand the role of CHD-related and typical stroke risk factors to ultimately guide management strategies to minimize stroke risk in the adult CHD population.

Aims

1) Estimate incidence of ischemic stroke in US cohort and by CHD type.

2) Identify patient-specific risk factors for ischemic stroke

3) Compare risk of ischemic stroke among patients who receive guidelines-based cardiac care to those who do not.

Vasoactive Selection in Pediatric Septic Shock and the Use of Cardiac Point-of-Care Ultrasound: A Retrospective Registry Analysis Across Multicenter Pediatric Emergency Medicine and Pediatric Critical Care

Pediatric septic shock requires rapid recognition of cardiovascular failure and timely treatment to restore adequate tissue perfusion. Vasoactive medications are central to management, yet considerable uncertainty remains regarding the optimal first‑line agent. Although guidelines recommend tailoring vasoactive choice to a…

Childhood Neighborhood Exposures and Pediatric Multiple Sclerosis

Question 1: How can we identify children with MS using ICD-10 codes in the PEDSnet dataset Question 2: How do neighborhood exposures influence the risk of pediatric MS development Aim 1: Validate a computable phenotype to identify pediatric MS. Aim…

Preventing Suicide among Sexual and Gender Diverse Youth

Suicide is the second leading cause of death among young adults in the United States. Sexual and gender diverse young adults (SGDYA) are at particularly high risk. SGDYA includes individuals who are lesbian, gay, bisexual, transgender, queer, or of another…

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