Variable Name

dx_malignancy

Created

Refreshed

2025-02

Development Code

Files

Tags

Validation Method

Data Model

PCORnet® Common Data Model
Created:2025-01
Documentation created by PCORnet® Network Partners for standardizing millions of data points from clinical information systems participating in the PCORnet® Network into a common format.

Funder(s)

Phenotype Description

A phenotype for identifying patients with malignancy based on cancer diagnoses and chemotherapy drug exposures.

Downloadable content for this Phenotype includes two R files (cohorts.R and driver.R) and a specs folder, which includes the related concept sets linked below.

Algothrithm Description

The malignancy computable phenotype will identify a cohort of patients meeting criteria for malignancy (cancer) based on diagnoses and drug exposures.

Inclusion Criteria

This phenotype employs a hierarchical inclusion criteria structure with three tiers. Patients are assessed for Criteria A, assessed for Criteria B if they do not meet Criteria A, and are assessed for Criteria C if they do not meet criteria for A or B. The criteria are:

  • A: >= 2 cancer diagnoses separated by >= 90 days
  • B: >= 2 chemotherapy exposures separated by >= 90 days AND >= 1 cancer diagnosis associated with a chemotherapy exposure
  • C: >= 1 cancer diagnosis and >= 1 chemotherapy exposure separated by >= 90 days AND >= 1 cancer diagnosis associated with a chemotherapy exposure
Exclusion Criteria

No explicit exclusion criteria are applied to this phenotype.

Development Population



Vocabulary

Clinical Subjects Headings

Provenance

Developed as part of the Preserving Kidney Function in Children with Chronic Kidney Disease (PRESERVE) study.

Preserving Kidney Function in Children with Chronic Kidney Disease (PRESERVE)
Study Dates:2021-07 - 2024-06Sponsor Site:PEDSnet Data Coordinating Center
Study intended to inform shared decision-making regarding blood pressure management for pediatric chronic kidney disease (CKD).

Published Research Applications

Related Concept Set

Cancer, Diagnosed
Refreshed:2022-12
This concept set is intended to identify patients with a diagnosis of cancer (malignancy).
Chemotherapy, Drug Exposure
Refreshed:2021-01
Concept set intended to identify patients with an exposure to chemotherapy.

Related Person

Related Phenotype

Related Code

Creative Commons license

Except where otherwised noted, this item's license is described as a CC-BY Attribution 4.0 license.