Chronic Kidney Disease (CKD) Etiology
Abstract
A function for identifying and categorizing chronic kidney disease (CKD) etiologies in a given cohort of patients.
Downloadable content for this Phenotype includes two R files (cohorts.R and driver.R) and a specs folder, which includes the related concept sets linked below.
Funder(s)
Provenance
Developed as part of the Preserving Kidney Function in Children with Chronic Kidney Disease (PRESERVE) study.
Description
This function will categorize each patient in a provided cohort into one of several different etiology groupings based on their CKD status and characterization. There are three different hierarchies available for classification:
- A 2-factor hierarchy classifying patients into glomerular or non-glomerular status;
- a 3-factor hierarchy classifying patients into malignant, glomerular disease, or other status;
- and a 4-factor hierarchy classifying patients into malignant, glomerular disease, other kidney disease, or other/non-specific statuses.
The malignant and glomerular disease statuses are identified using their associated phenotypes, while the “other kidney disease” status is identified using a concept set.
Vocabulary
Related Publications
Creative Commons license
Except where otherwised noted, this item's license is described as a CC-BY Attribution 4.0 license.