The Urinary Stone Disease Hub (USDHub) is an innovative research initiative designed to advance the understanding, treatment, and prevention of urinary stone disease (USD), a condition that affects over 11% of the U.S. population and incurs healthcare costs exceeding $10 billion annually. USDHub aims to address key barriers in USD research, such as the lack […]
Acute kidney injury (AKI) is defined as an abrupt loss of kidney function and is very common in children with chronic kidney disease (CKD). AKI is associated with high mortality rates in children and is thought to be a risk factor for a permanent loss of kidney function and development of end stage kidney disease. […]
The All of Us Research Program (https://allofus.nih.gov) is a national initiative that is enrolling participants who reflect the diversity of the United States, to build the largest and most diverse biomedical research repository. Recently, the All of Us Research program started a new initiative to enroll at least 150,000 pediatric participants to build a diverse […]
The “Extreme Weather and Pediatric Health Outcomes” study investigates the impact of climate change-related extreme weather events, such as extreme heat and heavy rainfall, on children’s health across the United States. This innovative research aims to address critical knowledge gaps by examining both short-term and long-term health outcomes in pediatric populations affected by extreme weather. […]
Organs are a limited resource that must be rationed. There are over 103,000 individuals on the national transplant waiting list in the United States and many will die while waiting for a transplant. Thus equitable allocation and responsible stewardship of transplanted organs is necessary 2. Kidney transplant outcomes can be adversely affected by risk factors […]
Kavita Dedhia is an assistant professor in otolaryngology at the University of Pennsylvania (UPENN) and Children’s Hospital of Philadelphia (CHOP). She has clinical expertise in pediatric otolaryngology, specifically chronic ear disease. Dr. Dedhia has recently completed the Master in Health Policy Research program at UPENN through which she gained introductory skills in study design and statistics. Her long-term goal […]
Sleep deficiency remains one of the most prominent and unaddressed public health concerns in pediatric healthcare settings. Pediatric sleep disparities are prominent across minoritized racial subpopulations in the dimensions of sleep duration, timing, alertness, behaviors, and quality/disorders. Despite the evidence of sleep deficiency burdening minoritized youth, these susceptible subpopulations are underrecognized in the clinical workflow […]
Several studies have found that infection with SARS-CoV-2 and COVID-19 diagnosis are associated with the development and progression of both Type 1 (T1D) and Type 2 Diabetes (T2D), possibly through infection of beta cells, increased insulin resistance, increased inflammation and fibrosis, and other biological processes. The proposed study will take advantage of robust existing infrastructure […]
Hypertension (HTN) is the primary cause of cardiovascular disease (CVD) in the United States. Individuals with the greatest risk of developing HTN in adulthood have elevated blood pressure (BP) and accelerated BP trajectories in childhood and adolescence, beginning at 9 years of age when BP tracking occurs, Social determinants of health (SDoH) drive 80% of […]
Sleep deficiency remains one of the most prominent and unaddressed public health concerns in pediatric healthcare settings. Pediatric sleep disparities are prominent across minoritized racial subpopulations in the dimensions of sleep duration, timing, alertness, behaviors, and quality/disorders. Despite the evidence of sleep deficiency burdening minoritized youth, these susceptible subpopulations are underrecognized in the clinical workflow […]